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Merck

855448

D-Leucine

99%, for peptide synthesis, ReagentPlus®

Synonym(s):

(R)-2-Amino-4-methylpentanoic acid

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
328-38-1
Molecular Weight:
131.17
NACRES:
NA.22
PubChem Substance ID:
24888380
UNSPSC Code:
12352209
EC Number:
206-327-7
MDL number:
MFCD00063088
Beilstein/REAXYS Number:
1721721

Key Documents

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Product Name

D-Leucine, ReagentPlus®, 99%

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1

InChI key

ROHFNLRQFUQHCH-RXMQYKEDSA-N

SMILES string

CC(C)C[C@@H](N)C(O)=O

product line

ReagentPlus®

assay

99%

form

powder (crystals)

optical activity

[α]23/D −14.7°, c = 2 in 5 M HCl

optical purity

ee: 97% (GLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

application(s)

peptide synthesis

Quality Level

100

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKBJ2904V
MKCP6849
MKCM2255
MKBZ1026V
MKBV5209V

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Mengxuan Chen et al.
Scientific reports, 8(1), 72-72 (2018-01-10)
Marine natural products are important resources for discovering novel anticancer drugs. In this study, an extract prepared from the culture of a sea anemone-derived actinomycete Streptomyces sp. ZZ406 in soluble starch and casein-related liquid medium was found to have activity
Brian T Wilhelm et al.
Nature protocols, 5(2), 255-266 (2010-02-06)
Next-generation sequencing technologies are revolutionizing genomics research. It is now possible to generate gigabase pairs of DNA sequence within a week without time-consuming cloning or massive infrastructure. This technology has recently been applied to the development of 'RNA-seq' techniques for
Shouji Takahashi et al.
Applied and environmental microbiology, 80(23), 7219-7229 (2014-09-14)
d-Amino acid oxidase (DAO) is a biotechnologically attractive enzyme that can be used in a variety of applications, but its utility is limited by its relatively poor stability. A search of a bacterial genome database revealed a gene encoding a
Adam L Hartman et al.
Neurobiology of disease, 82, 46-53 (2015-06-10)
There are no effective treatments for millions of patients with intractable epilepsy. High-fat ketogenic diets may provide significant clinical benefit but are challenging to implement. Low carbohydrate levels appear to be essential for the ketogenic diet to work, but the
Yazmin Macotela et al.
PloS one, 6(6), e21187-e21187 (2011-07-07)
Environmental factors, such as the macronutrient composition of the diet, can have a profound impact on risk of diabetes and metabolic syndrome. In the present study we demonstrate how a single, simple dietary factor--leucine--can modify insulin resistance by acting on

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