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Merck

900622

Gelatin methacryloyl

gel strength 300 g Bloom, degree of substitution 60%

Synonym(s):

GelMA, Gelatin methacrylamide, Gelatin methacrylate, GelMa, Gelatin Methacrylate, Gelatin / GelMA & derivatives

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About This Item

Linear Formula:
(C40H59N11O13)n
NACRES:
NA.23
UNSPSC Code:
12352202
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Quality Level

form

powder

storage temp.

2-8°C

Application

Gelatin methacryloyl can be used to form cross-linked hydrogels for tissue engineering and 3D printing. It has been used for endothelial cell morphogenesis, cardiomyocytes, epidermal tissue, injectable tissue constructs, bone differentiation, and cartilage regeneration. Gelatin methacryloyl has been explored in drug delivery applications in the form of microspheres and hydrogels.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protocols

Frequently asked questions (FAQs) for KAPA SYBR® FAST One-Step qRT-PCR Kits.

Articles

Shrike Zhang教授(Harvard Medical School、米国)が、in vitroの薬物試験のための3Dバイオプリンティング組織モデルの進展について述べ、バイオインクの選択基準と組織モデルのバイオファブリケーションにおける3Dバイオプリンティングの応用例を紹介します。

高分解能の3Dプリンティングを含むバイオファブリケーションに向けたゼラチン-メタクリルアミド(GelMA)などの光架橋性誘導体などを紹介します。

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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Related Content

組織工学では、損傷した組織を修復または置き換えるために、体内の微小環境を模倣して、足場、生きた細胞、生物学的活性分子から組織を構築します。

Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

ゼラチンメタクリロイルは、複合ヒドロゲルプラットフォームを作製するために広く使用されている材料です。


Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization
Kristel W M Boere et al.
Acta biomaterialia, 10(6), 2602-2611 (2014-03-05)
Hydrogels can provide a suitable environment for tissue formation by embedded cells, which makes them suitable for applications in regenerative medicine. However, hydrogels possess only limited mechanical strength, and must therefore be reinforced for applications in load-bearing conditions. In most
Mehdi Nikkhah et al.
Biomaterials, 33(35), 9009-9018 (2012-09-29)
Engineering of organized vasculature is a crucial step in the development of functional and clinically relevant tissue constructs. A number of previous techniques have been proposed to spatially regulate the distribution of angiogenic biomolecules and vascular cells within biomaterial matrices