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Merck

900628

Gelatin methacryloyl

gel strength 90-110 g Bloom, degree of substitution 60%

Synonym(s):

GelMA, Gelatin methacrylamide, Gelatin methacrylate, GelMa, Gelatin Methacrylate

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About This Item

Linear Formula:
(C40H59N11O13)n
NACRES:
NA.23
UNSPSC Code:
12352202
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Product Name

Gelatin methacryloyl, gel strength 90-110 g Bloom, degree of substitution 60%

form

solid

storage temp.

2-8°C

Quality Level

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Application

Gelatin methacrylate can be used to form cross-linked hydrogels for tissue engineering and 3D printings. It has been used for endothelial cell morphogenesis, cardiomyocytes, epidermal tissue, injectable tissue constructs, bone differentiation, and cartilage regeneration. Gelatin-methacrylate has been explored in drug delivery applications in the form of microspheres and hydrogels.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization
Kristel W M Boere et al.
Acta biomaterialia, 10(6), 2602-2611 (2014-03-05)
Hydrogels can provide a suitable environment for tissue formation by embedded cells, which makes them suitable for applications in regenerative medicine. However, hydrogels possess only limited mechanical strength, and must therefore be reinforced for applications in load-bearing conditions. In most
Mehdi Nikkhah et al.
Biomaterials, 33(35), 9009-9018 (2012-09-29)
Engineering of organized vasculature is a crucial step in the development of functional and clinically relevant tissue constructs. A number of previous techniques have been proposed to spatially regulate the distribution of angiogenic biomolecules and vascular cells within biomaterial matrices
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV, et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Heemin Kang et al.
Acta biomaterialia, 10(12), 4961-4970 (2014-08-26)
Human induced pluripotent stem cells (hiPSC) are a promising cell source with pluripotency and self-renewal properties. Design of simple and robust biomaterials with an innate ability to induce lineage-specificity of hiPSC is desirable to realize their application in regenerative medicine.

Articles

Shrike Zhang教授(Harvard Medical School、米国)が、in vitroの薬物試験のための3Dバイオプリンティング組織モデルの進展について述べ、バイオインクの選択基準と組織モデルのバイオファブリケーションにおける3Dバイオプリンティングの応用例を紹介します。

高分解能の3Dプリンティングを含むバイオファブリケーションに向けたゼラチン-メタクリルアミド(GelMA)などの光架橋性誘導体などを紹介します。

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Protocols

Frequently asked questions (FAQs) for KAPA SYBR® FAST One-Step qRT-PCR Kits.

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ゼラチンメタクリロイルは、複合ヒドロゲルプラットフォームを作製するために広く使用されている材料です。

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