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Merck

904759

Polyethylenimine, branched

average Mw ~270,000 by LS

Synonym(s):

PEI

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About This Item

Linear Formula:
H(NHCH2CH2)nNH2
CAS Number:
9002-98-6
UNSPSC Code:
12162002
MDL number:
MFCD00084427

Key Documents

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description

Identity:Conforms to structure

assay

>93% (KFT)

form

liquid

mol wt

~90 kDa by LS, average Mw ~270,000 by LS

color

colorless to pale yellow

bp

250 °C (lit.)

SMILES string

C1CN1

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChI key

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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Application

Branched polyethyleneimine (PEI) is widely used in many applications due to its polycationic character. Unlike its linear equivalent, branched PEI contains primary, secondary, and tertiary amines. Primarily utilized in industrial applications, high molecular weight PEI has been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture.
Polyethylenimine, branched (PEI) is a hydrophilic polymer and a gene carrier, which can be conjugated with dextran to enhance the stability of polycationic vectors. It is also used in the preparation of cationic poly(lactic-co-glycolic acid) (PLGA) nanoparticles for potential usage in gene therapy. PEI can also be grafted on polyacrylonitrile (PAN) fiber membrane for the removal of hexavalent chromium (VI) from wastewater.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

904759-1KG: + 904759-250G: + 904759-100G: + 904759-BULK: + 904759-VAR:

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Improved stability of polycationic vector by dextran-grafted branched polyethylenimine
Tseng W and Jong C
Biomacromolecules, 4(5), 1277-1284 (2003)
Branched polyethylenimine grafted electrospun polyacrylonitrile fiber membrane: a novel and effective adsorbent for Cr (VI) remediation in wastewater
Zhao R, et al.
Journal of Material Chemistry A, 5(3), 1133-1144 (2017)
Polyethylenimine Applications in Carbon Dioxide Capture and Separation: From Theoretical Study to Experimental Work
Shen X, et al.
Energy Technology, 5, 822 -8833 (2017)
Polyethyleneimine-nano silica composites: a low-cost and promising adsorbent for CO2 capture
Li K, et al.
Journal of Material Chemistry A, 3, 2166-2175 (2015)
Biodegradable nanoparticles modified by branched polyethylenimine for plasmid DNA delivery
Son S and Kim WJ
Biomaterials, 31(1), 133-143 (2010)

Articles

腫瘍標的化のためのナノ粒子薬物および遺伝子送達

Professor Katayamaは、EPR効果を利用した薬物送達システムについて、新素材による刺激応答性システムに焦点を当てて説明しています。

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

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