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850104P

Avanti

18:0 Lyso PI

Avanti Research™ - A Croda Brand

Synonym(s):

1-octadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(18:0/0:0); 110719

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About This Item

Empirical Formula (Hill Notation):
C27H56NO12P
CAS Number:
849412-49-3
Molecular Weight:
617.71
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

18:0 Lyso PI, 1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

assay

>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850104P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850104P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850104P

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C27H53O12P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(29)37-18-20(28)19-38-40(35,36)39-27-25(33)23(31)22(30)24(32)26(27)34;/h20,22-28,30-34H,2-19H2,1H3,(H,35,36);1H3/t20-,22-,23-,24+,25-,26-,27-;/m1./s1

InChI key

QVEDYTZLCBLSCH-FJYNCLFYSA-N

General description

Lysophosphatidylinositol (LPI), an acidic lysophosholipid, carries inositol in its head group.

Application

18:0 Lyso PI (1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as lysophosphatidylinositol (LPI) substrate in lysophosphatidylinositol acyltransferase biochemical assay to determine lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may be used as a synthetic LPI to compare its effects with liver LPI in transferrin (Tf) endocytosis. It may also be used as LPI standard to quantify serum LPI levels in gonadectomized rats.

Biochem/physiol Actions

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) displays mitogenic activity and can serve as a bioactive lysophospholipid mediator. It may be considered as a lipid mediator.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850104P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850104P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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