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Merck

850697C

Avanti

06:0 PE

Avanti Research - A Croda Brand

Synonym(s):

PE(6:0/6:0)

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About This Item

Empirical Formula (Hill Notation):
C17H34NO8P
CAS Number:
Molecular Weight:
411.43
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

06:0 PE, 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, chloroform

InChI

1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1

InChI key

PELYUHWUVHDSSU-OAHLLOKOSA-N

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850697C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850697C

concentration

10 mg/mL (850697C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Application

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
  • as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity studies as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
  • as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
  • as calibration standard in hydrophilic interaction liquid chromatography (HILIC) and ion mobility (IM)

Biochem/physiol Actions

Phosphoethanolamine (PE) is known to possess antitumor activity and inhibitory effects on tumor progression in vivo. It also exhibits antiproliferative and proapoptotic effects. It acts as a precursor of phosphatidylcholine and phosphatidylethanolamine.

General description

06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) is a phosphoethanolamine (PE) molecule which carries short acyl chains. It is an ethanolamine-type substrate and a water-soluble phospholipid.

Packaging

5 mL Clear Glass Sealed Ampule (850697C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3


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Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity
Lorenzo VP, et al.
Journal of Chemistry (2020)
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL

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