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About This Item
Empirical Formula (Hill Notation):
C21H42O7PNa
CAS Number:
Molecular Weight:
460.52
UNSPSC Code:
51191904
NACRES:
NA.25
description
1-stearoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
assay
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
form
powder
packaging
pkg of 1 × 25 mg (857128P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
InChI key
YJQFVAZHPIBPHN-VEIFNGETSA-M
General description
Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells. 18:0 Lyso PA has stearic acid at sn-1 and a hydroxyl group at sn-2 position.
Application
18:0 Lyso PA is suitable for use:
- to determine the extraction recovery of LPA at neutral pH and acidic pH by chromatographic method
- to use as internal standard to study the role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
- to investigate its effects on clathrin?dependent endocytosis
Biochem/physiol Actions
Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).
Packaging
5 mL Amber Glass Screw Cap Vial (857128P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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