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860527P

Avanti

C24 Ceramide-1-Phosphate (d18:1/24:0)

Name: C24 Ceramide-1-Phosphate (d18:1/24:0)
Brand: AVANTI

Avanti Research^™ - A Croda Brand

Synonym(s):

N-lignoceroyl-ceramide-1-phosphate (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):

C₄₂H₈₇N₂O₆P

CAS Number:

1246303-20-7

Molecular Weight:

747.12

UNSPSC Code:

12352211

NACRES:

NA.25

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Properties

Product Name

C24 Ceramide-1-Phosphate (d18:1/24:0), Avanti Research^™ - A Croda Brand 860527P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860527P-1mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 860527P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)COP([O-])(O)=O.[NH4+]

InChI key

JGGZHGYBRJNAOW-FHPBFELKSA-N

Description

General description

Ceramide 1-phosphate (C1P) is a sphingolipid analog of phosphatidate.

Application

C24 Ceramide-1-Phosphate (d18:1/24:0) or N-lignoceroyl-ceramide-1-phosphate (ammonium salt) has been used as a standard to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2).

Biochem/physiol Actions

Ceramide 1-phosphate (C1P) is a mitogenic agent, which has antiapoptotic and prosurvival activities. It negatively regulates tumor necrosis factor-α (TNFα) production stimulated by lipopolysaccharide. C1P also mediates inflammatory response and aids in phagocytosis. It is considered as a second lipid messenger of agonist-stimulated sphingomyelin metabolism.

Packaging

5 mL Amber Glass Screw Cap Vial (860527P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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