03-0154-00
SMC® Human cTnI High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of cTnI in human serum and plasma samples
동의어(들):
Cardiac Muscle Troponin I immunoassay kit, Cardiac Troponin I immunoassay kit, cTnI Single Molecule Counting Kit, cTnI ultra-sensitive immunoassay
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.84
UNSPSC Code:
12161503
Species reactivity:
human
Technique(s):
single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with for use with FemtoQuest™ and SMCxPRO® instruments
제품 이름
SMC® Human cTnI High Sensitivity Immunoassay Kit,
description
Used for ultrasensitive quantification of cTnI in human serum and plasma samples
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
serum
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
Cardiac Troponin I (cTnI) is a regulatory protein found in cardiac muscle tissue and plays a critical role in muscle contraction. It is released into the bloodstream following myocardial injury, making it a highly specific and sensitive biomarker for cardiac muscle damage. Elevated levels of cTnI are a key indicator of acute myocardial infarction (AMI) and are widely used in the diagnosis and risk stratification of patients with suspected acute coronary syndrome (ACS). Due to its high cardiac specificity and prolonged elevation post-injury, cTnI is considered a gold-standard biomarker for detecting even minor myocardial damage. High-sensitivity assays enable earlier detection of cardiac events, improving clinical decision-making and patient outcomes.
Features and Benefits
- Ultra-Low Detection Limits: Enables femtogram-level detection of cardiac troponin I, allowing early identification of myocardial injury.
- Expanded Dynamic Range: Accurately quantifies both baseline and elevated cTnI levels, supporting a wide range of research applications.
- Targeted Research Applications: Ideal for studies in cardiovascular disease, drug-induced cardiotoxicity, and cardiac safety assessment.
- Streamlined Lab Operations: Automation-compatible reagents reduce manual handling and improve workflow efficiency.
- Robust Performance: Delivers consistent, high-quality results for preclinical and translational research.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 690 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 170-600,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 80% Plasma: 85%
- Recovery: Plasma: 119%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Cardiovascular
Other Notes
Although cTnI was detectable in non-human primate, mouse, rat, canine and equine samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Danger
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B