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Merck

1.00397

N,N-Dimethylformamide

for peptide synthesis

Synonym(s):

DMF, N,N-Dimethylmethanamide, Formic acid dimethylamide, DMF, NSC 5356

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About This Item

Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
UNSPSC Code:
12352111
NACRES:
NA.22
EC Index Number:
200-679-5
MDL number:
Beilstein/REAXYS Number:
605365
Assay:
≥99.9% (GC)
Bp:
153 °C (lit.)
Vapor pressure:
2.7 mmHg ( 20 °C)
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Quality Level

vapor pressure

2.7 mmHg ( 20 °C)

assay

≥99.9% (GC)

form

liquid

autoignition temp.

833 °F

potency

3010 mg/kg LD50, oral (Rat), 1500 mg/kg LD50, skin (Rabbit)

expl. lim.

15.2 %

dilution

(for synthesis)

impurities

≤0.0002 meq/g Alkalinity, ≤0.0005 meq/g Acidity, ≤10 ppm Amines (Dimethylamine), ≤300 ppm Water

color

APHA: ≤10

pH

7 (20 °C, 200 g/L in H2O)

bp

153 °C (lit.)

mp

−61 °C (lit.)

transition temp

flash point 57.5 °C

solubility

soluble 1000 g/L

density

0.944 g/mL (lit.)

application(s)

peptide synthesis

storage temp.

2-30°C

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Application

Solvent for many hydrophobic organic compounds.

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Color: ≤ 10 Hazen
Acidity: ≤ 0.0005 meq/g
Alkalinity: ≤ 0.0002 meq/g
Amines (Dimethylamine): ≤ 10 ppm
Evaporation residue: ≤ 10
Water: ≤ 300 ppm

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

135.5 °F - closed cup

flash_point_c

57.5 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

Class I Designated Chemical Substances

prtr

1003971000: + 1003976025: + 1003974004: + 1003974000: + 1003979030: + 1003970000: + 1003974024: + 1003979185: + 1003976190: + 1003972500: + 1003979010:

jan

Group 4: Flammable liquids + Type 2 petroleums + Hazardous rank III + Water soluble liquid

fsl


Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
1.00397.400004027269261665
1.00397.250004027269261658

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