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1.07478

1,2-Propanediol

EMPROVE® EXPERT, Ph. Eur., BP, USP, ChP

Synonym(s):

1,2-Propanediol, 1,2-Propylene glycol

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About This Item

Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
57-55-6
Molecular Weight:
76.09
UNSPSC Code:
12352104
EC Index Number:
200-338-0
MDL number:
MFCD00064272
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Quality Segment

500

agency

BP, ChP, Ph. Eur., USP

vapor pressure

0.11 hPa ( 20 °C)

product line

EMPROVE® EXPERT

assay

≥99.5% (GC)

form

liquid

autoignition temp.

371 °C

expl. lim.

2.4-17.4 % (v/v)

refractive index

n20/D 1.43

pH

6-8 (20 °C, 100 g/L in H2O)

bp

188 °C/1013 hPa

mp

-59 °C

transition temp

flash point 99 °C

density

1.04 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
parenterals
parenterals
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

SMILES string

OC(CO)C

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propylene glycol is used as solvent in a variety of liquid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

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