Skip to Content
Merck

Key Documents

View All Documentation

12668-M

Albumin, Human Serum, Fraction V

Synonym(s):

Albumin, Human Serum, Fraction V

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

CAS Number:
70024-90-7
UNSPSC Code:
12352202
MDL number:
MFCD00081418
NACRES:
NA.25
Assay:
≥95% (SDS-PAGE)
Form:
solid
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

description

Merck USA index - 14, 8468

Quality Level

100

assay

≥95% (SDS-PAGE)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: 20 mg/mL

storage temp.

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

General description

Human serum albumin (HSA), a globular, soluble, and unglycosylated monomeric protein, is the most abundant protein in the plasma. It is a multidomain protein consisting of three homologous domains, named I, II, and III. Each of these domains contains subdomains A and B possessing common structural motifs. The HSA gene is present on the human chromosome location 4q13.3.

Biochem/physiol Actions

Human serum albumin (HSA) serves as a carrier protein for fatty acids, thyroid hormones, and steroids. It plays a critical role in stabilizing extracellular fluid volume. HSA acts as an excipient for vaccines and therapeutic protein drugs. It is also used as a cell culture medium supplement to produce vaccines and pharmaceuticals. HSA is used to treat hemodialysis, acute liver failure, chronic liver disease. HSA has importance in biological applications, such as ligand trapping, nano delivery of drugs, and fusion proteins.

Preparation Note

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

12668-10GM: + 12668-GM: + 12668-100GM-M: + 12668-10GM-M: + 12668-100GM:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yang He et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(47), 19078-19083 (2011-11-02)
Human serum albumin (HSA) is widely used in clinical and cell culture applications. Conventional production of HSA from human blood is limited by the availability of blood donation and the high risk of viral transmission from donors. Here, we report
Gabriella Fanali et al.
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity

Global Trade Item Number

SKUGTIN
12668-10GMCN04055977222098
12668-100GMCN04055977222104