Skip to Content
Merck

14-455

Rap1 Assay Reagent (Ral GDS-RBD, agarose), 650 µg

Reagent (Ral GDS-RBD, agarose). A GST-tagged fusion protein, corresponding to amino acids 788-884 of human Ral GDS-Rap binding domain (RBD), for use in Affinity Binding Assays.

Synonym(s):

Ral GDS-RBD Assay Reagent, Rap1 Detection Reagent

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352204
NACRES:
NA.41
eCl@ss:
32160405
Form:
liquid
Biological source:
human

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

human

form

liquid

manufacturer/tradename

Upstate®

technique(s)

affinity binding assay: suitable

NCBI accession no.

NM_018975.2

UniProt accession no.

Q9NYB0

shipped in

dry ice

Quality Level

100

Gene Information

human ... TERF2IP(54386)

General description

A GST-tagged fusion protein, corresponding to amino acids 788-884 of human Ral GDS-Rap binding domain (RBD)
Product Source: expressed in E. coli

Preparation Note

6 months at -20C

Analysis Note

routinely evaluated by immunoblot analysis

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

14-455:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Amlodipine potentiates metalloproteinase activity and accelerates elastin degradation in a model of aneurysmal disease.
J R Boyle,I M Loftus,S Goodall,M Crowther,P R Bell,M M Thompson
European Journal of Vascular and Endovascular Surgery null
Measurement of GTP-bound Ras-like GTPases by activation-specific probes.
M van Triest et al.
Methods in enzymology, 333, 343-348 (2001-06-13)
B Franke et al.
The EMBO journal, 16(2), 252-259 (1997-01-15)
Rap1 is a small, Ras-like GTPase whose function and regulation are still largely unknown. We have developed a novel assay to monitor the active, GTP-bound form of Rap1 based on the differential affinity of Rap1GTP and Rap1GDP for the Rap
J F Rebhun et al.
The Journal of biological chemistry, 275(45), 34901-34908 (2000-08-10)
Although the Ras subfamily of GTPases consists of approximately 20 members, only a limited number of guanine nucleotide exchange factors (GEFs) that couple extracellular stimuli to Ras protein activation have been identified. Furthermore, no novel downstream effectors have been identified
Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
Herrmann, C, et al
The Journal of Biological Chemistry, 271, 6794-6800 (1996)
View All Related Papers

Global Trade Item Number

SKUGTIN
14-45504053252469350
17-32104053252369438

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service