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Merck

343333

5-Fluoro-2′-deoxyuridine

≥98% (HPLC), solid, thymidylate synthase inhibitor, Calbiochem®

Synonym(s):

5-Fluoro-2′-deoxyuridine, FdUrd, FUdR, 5-FdU, Floxuridine

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About This Item

Empirical Formula (Hill Notation):
C9H11FN2O5
CAS Number:
50-91-9
Molecular Weight:
246.19
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00006530

Key Documents

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Product Name

5-Fluoro-2′-deoxyuridine, Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

SMILES string

Fc1[c]([nH][c]([n](c1)[C@@H]2O[C@@H]([C@H](C2)O)CO)=O)=O

InChI

1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

InChI key

ODKNJVUHOIMIIZ-RRKCRQDMSA-N

description

Merck USA index - 14, 4112

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

aqueous buffer: 1 mg/mL
water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Cell permeable: no
Primary Target
Experimental anticancer agent
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

General description

Experimental anti-cancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.
Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Nakagama, H., et al. 2001. Jpn. J. Clin. Oncol.31, 251.
Malmberg, M., et al. 1993. Cell Prolif. 26, 291.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Biomedicines, 10(3) (2022-03-26)
Neurotrophins are growth factors that exert important neuroprotective effects by preventing neuronal death and synaptic loss. Nerve Growth Factor (NGF) acts through the activation of its high-affinity, pro-survival TrkA and low-affinity, pro-apoptotic p75NTR receptors. NGF has been shown to slow

Global Trade Item Number

SKUGTIN
343333-50MGCN04055977195118

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