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Merck

3570

Glycine

Synonym(s):

Glycine, Gly, Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
56-40-6
Molecular Weight:
75.07
NACRES:
NA.54
UNSPSC Code:
12352209
Beilstein/REAXYS Number:
635782
MDL number:
MFCD00008131

Key Documents

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SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

description

RTECS - MB7600000
Merck USA index - 14, 4491

assay

>99% (by assay)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤100 CFU/g Total microorganism
≤6.0 EU/g Endotoxin

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

water: 250 mg/mL

cation traces

Fe: ≤10 ppm
heavy metals (as Pb): ≤5 ppm

shipped in

ambient

storage temp.

15-25°C

Quality Level

100

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Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Disclaimer

Toxicity: Standard Handling (A)

General description

A non-essential, optically inactive, non-chiral amino acid. It is the smallest of the 20 natural amino acids. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.
A nonpolar, uncharged amino acid.

Other Notes

Shapiro, S. 1997. Neurosurgery 40, 168.
Mount, H., et al. 1991. Mol. Pharmacol.39, 205.
Thompson, A.M., et al. 1989. Nature338, 422.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
3570-1KGCN04055977192834
3570-500GMCN07790788049553

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