Skip to Content
Merck

420321

KT5823

≥98% (HPLC), Protein Kinase G inhibitor, solid

Synonym(s):

KT5823, PKG Inhibitor VII

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C29H25N3O5
CAS Number:
126643-37-6
Molecular Weight:
495.53
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD09878278

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

KT5823, Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).

SMILES string

[n]21c3c4[n](c6c(c4c7c(c3c8c2cccc8)CN(C7=O)C)cccc6)[C@@H]5O[C@]1([C@@](C5)(OC)C(=O)OC)C

InChI

1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3/t20-,28+,29+/m1/s1

InChI key

QTYMDECKVKSGSM-YMUMJAELSA-N

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 1 mg/mL, DMF: soluble

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Highly specific cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM). Inhibits protein kinase C (Ki = 4.0 µM) and protein kinase A (Ki >10.0 µM) at higher concentrations.
Highly specific, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase G (Ki = 234 nM).

Biochem/physiol Actions

Cell permeable: yes
Primary Target
PKG
Product competes with ATP.
Reversible: yes
Target Ki: 234 nM against protein kinase G

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Further dilute with aqueous buffers just prior to use.

Other Notes

Grider, J.R. 1993. Am. J. Physiol.264, G334.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

420321-100UG: + 420321-50UG: + 420321-UG: + 420321-5MG:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
420321-100UGCN04055977211047
420321-50UGCN04055977211054

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service