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Merck

524628

Phosphatase Inhibitor Cocktail IV

liquid, for the inhibition of serine/threonine and alkaline phosphatases

Synonym(s):

Phosphatase Inhibitor

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.54
Form:
liquid
Solubility:
water: soluble
Storage temp.:
−20°C
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Product Name

Phosphatase Inhibitor Cocktail Set IV, Phosphatase inhibitor Cocktail Set IV is a cocktail of three phosphatase inhibitors for the inhibition of both serine/threonine and alkaline phosphatases.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

solubility

water: soluble

shipped in

wet ice

storage temp.

−20°C

General description

A cocktail of three phosphatase inhibitors specially formulated for inhibition of alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A. May be used with cell lysates and tissue extracts, including extracts containing detergents. Supplied as 1 ml or a set of five 1 ml vials. Each vial contains 1 ml phosphatase inhibitor cocktail solubilized in 95% DMSO, consisting of the following components:

Biochem/physiol Actions

Cell permeable: no
Primary Target
Serine/threonine and alkaline phosphatases
Product does not compete with ATP.
Reversible: no

Physical form

In 95% DMSO.

Preparation Note

For long-term storage, aliquot and freeze (-20°C). Dilute 1:50 just prior to use.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - (refers to pure substance)

flash_point_c

87 °C - (refers to pure substance)


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water insoluble liquid

fsl



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chunwan Lu et al.
Oncogene, 41(18), 2651-2662 (2022-03-31)
The role of glucose-6-phosphate dehydrogenase (G6PD) in human cancer is incompletely understood. In a metabolite screening, we observed that inhibition of H3K9 methylation suppressed aerobic glycolysis and enhances the PPP in human mesothelioma cells. Genome-wide screening identified G6PD as an
Heeju Han et al.
Scientific reports, 12(1), 6416-6416 (2022-04-21)
Post-inflammatory hyperpigmentation is a skin discoloration process that occurs following an inflammatory response or wound. As the skin begins to heal, macrophages first exhibit a proinflammatory phenotype (M1) during the early stages of tissue repair and then transition to a
Kenneth D'Souza et al.
Nutrients, 12(2) (2020-02-12)
Deregulation of lipid metabolism and insulin function in muscle and adipose tissue are hallmarks of systemic insulin resistance, which can progress to type 2 diabetes. While previous studies suggested that milk proteins influence systemic glucose homeostasis and insulin function, it



Global Trade Item Number

SKUGTIN
524628-1MLCN07790788051082
524628-1SETCN07790788051099