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Merck

8.03060

N,N-Dimethylaniline

for synthesis

Synonym(s):

N,N-Dimethylaniline, Dimethylaminobenzene

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About This Item

Linear Formula:
C6H5N(CH3)2
CAS Number:
Molecular Weight:
121.18
UNSPSC Code:
12352116
EC Index Number:
204-493-5
NACRES:
NA.22
MDL number:
Assay:
≥99% (GC)
Form:
liquid
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vapor pressure

0.53 hPa ( 20 °C)

Quality Level

assay

≥99% (GC)

form

liquid

autoignition temp.

370 °C (DIN 51794)

potency

1120 mg/kg LD50, oral (Rat), 1700 mg/kg LD50, skin (Rabbit)

expl. lim.

1.2-7 % (v/v)

pH

7.4 (20 °C, 1.2 g/L in H2O)

bp

192-195 °C/1013 hPa

mp

2.5 °C

transition temp

flash point 75 °C

solubility

1.2 g/L

density

0.96 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

N(C)(C)c1ccccc1

InChI

1S/C8H11N/c1-9(2)8-6-4-3-5-7-8/h3-7H,1-2H3

InChI key

JLTDJTHDQAWBAV-UHFFFAOYSA-N

Application

<ul>
<li><strong>Dual Fluorescence Bioimaging:</strong> N,N-Dimethylaniline derivatives to develop NIR-II emissive donor-acceptor-donor fluorophores. These compounds are used for dual fluorescence bioimaging and photothermal therapy applications, illustrating the critical role of N,N-Dimethylaniline in the development of new biomedical imaging agents (Sparks et al., 2024).</li>
<li><strong>Real-Time Monitoring of Biomolecules: </strong>Dimethylaniline is used in the construction of a fluorescent probe for in vivo real-time imaging and inhibition of A and beta;-fibril formation (Chen et al., 2024).</li>
<li><strong><strong>Photoinduced Electron Transfer Studies: </strong></strong>N,N-dimethylaniline is used in the quenching of the S1 state of two polar dyes, coumarin 152a and Nile red (Verma et al., 2024).</li>
</ul>

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.955 - 0.957
Identity (IR): passes test


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

167.0 °F - closed cup

flash_point_c

75 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class II Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

8030602501: + 8030609035: + 8030601000: + 8030600000: + 8030602500: + 8030609999: + IN28030609025: + 8030600521: + 8030602521: + IN28030600500: + 8030600500: + 8030600501: + 8030600100:

jan



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