8.08260
Trifluoroacetic acid
for synthesis
Synonym(s):
TFA
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About This Item
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
SMILES string
OC(C(F)(F)F)=O
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
grade
synthesis grade
vapor density
3.9 (vs air)
vapor pressure
97.5 mmHg ( 20 °C)
assay
≥99% (acidimetric)
form
liquid
dilution
(for synthesis)
refractive index
n20/D 1.3 (lit.)
pH
1 (10 g/L in H2O)
bp
72.4 °C (lit.)
mp
−15.4 °C (lit.)
solubility
soluble 10 g/mL
density
1.489 g/mL at 20 °C (lit.)
storage temp.
2-30°C
Quality Level
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Analysis Note
Density (d 20 °C/ 4 °C): 1.487 - 1.490
Identity (IR): passes test
Application
- In the direct conversion of cyclohexanone to caprolactam using acetonitrile as the additive.
- In the synthesis of 1,2,4,5-tetrasubstituted imidazoles by four-component condensation of benzil, aldehydes, amines, and ammonium acetate.
- In the synthesis of d-α-Tterpineo from d-limonene by Markovnikov addition followed by hydrolysis.
Features and Benefits
- High acidity
- Easy elimination
- Good solubility in organic solvent and in water.
General description
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
>212.0 °F - Pensky-Martens closed cup
flash_point_c
> 100 °C - Pensky-Martens closed cup
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
Substances Subject to be Indicated Names
ishl_indicated
Substances Subject to be Notified Names
ishl_notified
8082600100: + 8082600521: + IN2RCMT808260: + 8082602501: + 8082600121: + 8082600025: + 8082609060: + 8082600500: + IN28082600100: + 8082600101: + 8082600501: + 8082600026: + 8082601000: + 8082601001: + 8082609025: + IN28082600500: + 8082602500: + IN28082602500: + 8082600000: + 8082609015: + 8082609999:
jan
Certificates of Analysis (COA)
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Protocols
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 8.08260.0026 | 04027269250652 |
| 8.08260.0101 | 04054839446597 |
| 8.08260.1001 | 04054839448881 |
| 8.08260.0501 | 04054839451539 |
| 8.08260.2501 | 04054839449628 |
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