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Merck

8.20261

8-Hydroxyquinoline

for synthesis

Synonym(s):

8-Hydroxyquinoline, Oxine, 8-Quinolinol

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
Molecular Weight:
145.16
UNSPSC Code:
12352104
EC Index Number:
205-711-1
NACRES:
NA.22
MDL number:
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Quality Level

assay

≥99.0% (GC)

form

solid

potency

1200 mg/kg LD50, oral (Rat)

reaction suitability

reaction type: Addition Reactions

bp

267 °C/1013 hPa

mp

72.5-74.0 °C

solubility

555 mg/L

density

1.034 g/cm3 at 20 °C

application(s)

peptide synthesis

storage temp.

2-30°C

SMILES string

n1c2c(ccc1)cccc2O

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChI key

MCJGNVYPOGVAJF-UHFFFAOYSA-N

Application

<ul>
<li><strong>8-Hydroxyquinoline in luminescent cocrystals for analytical detection:</strong> 8-Hydroxyquinoline is used as an electron donor during the development of luminescent organic cocrystal for the detection of 2,4-dinitroaniline, demonstrating its utility in analytical chemistry applications (Liu et al., 2024).</li>
<li><strong>Extraction and determination of pesticides using 8-Hydroxyquinoline functionalized nanocomposites:</strong> Poly(8-hydroxyquinoline) were utilized for the extraction and determination of organophosphorus pesticides in various environmental samples, showcasing its application in environmental monitoring (Shahsavani and Fakhari, 2024).</li>
<li><strong>8-Hydroxyquinoline in medical imaging and therapy:</strong> 8-Hydroxyquinoline is used as a Schiff base derivative and an auxiliary ligand in the synthesis of the dinuclear lanthanide complex [Ho2(L)2(acac)2(CH3OH)2] (Cong et al., 2024).</li>
</ul>

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 71 °C
Melting range (upper value): ≤ 74 °C
Identity (IR): passes test


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Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
8.20261.025004022536455365
8.20261.100004022536455372