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Merck

MSHMAG-21K

MILLIPLEX® Multi-Species Hormone Panel

Configurable Multi-Species Hormone 6-Plex Panel

Synonym(s):

luminex multiple species thyroid reproductive stress endocrine metabolic hormones multiplex assay, millipore multiple species metabolism hormones multiplex kit, multi species hormone immunoassay panel

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.47

Key Documents

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Quality Level

200

species reactivity

hamster, rat, human, cat, horse, dog, guinea pig, rabbit, rhesus monkey, monkey (cynomolgous), mouse

manufacturer/tradename

Milliplex®

packaging

1 ea of

assay range

accuracy: 105%
(Canine Samples: T3)
accuracy: 80%
(Canine Samples: Estradiol)
accuracy: 85%
(Human Samples: Progesterone)
accuracy: 87%
(Canine Samples: T4)
sensitivity: 0.01 ng/mL
(MinDC+2SD; Estradiol)
sensitivity: 0.12 ng/mL
(MinDC+2SD; T3)
sensitivity: 0.25 ng/mL
(MinDC+2SD; Progesterone)
sensitivity: 0.33 ng/mL
(MinDC+2SD; Cortisol)
sensitivity: 0.51 ng/mL
(MinDC+2SD; T4)
standard curve range: 0.014-10 ng/mL
(Estradiol)
standard curve range: 0.07-50 ng/mL
(T3)
standard curve range: 0.14-100 ng/mL
(Progesterone)
standard curve range: 0.27-200 ng/mL
(Cortisol)
standard curve range: 0.34-250 ng/mL
(T4)
inter-assay cv: <10%
intra-assay cv: <10%
(Cortisol)
inter-assay cv: <15%
intra-assay cv: <10%
(Estradiol)
inter-assay cv: <15%
intra-assay cv: <10%
(Progesterone)
inter-assay cv: <15%
intra-assay cv: <10%
(T3)
inter-assay cv: <15%
intra-assay cv: <10%
(T4)

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

General description

Cortisol reflects stress response and adrenal function. Estradiol, progesterone, and testosterone regulate reproductive physiology. T3 and T4 are essential for metabolic rate and thyroid function. Together, these hormones provide a comprehensive view of endocrine health across species.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes across multiple species using serum, plasma, tissue lysates, or tissue/cell culture supernatants.

Analytes Included: Cortisol, Estradiol, Progesterone, T3, T4, Testosterone Note: This is a competitive assay. This assay requires an extraction step for serum and plasma samples (instructions are provided in the kit protocol).

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Biochem/physiol Actions

Cross Reactivty
Approximately 10% cross-reactivity to Cortisol is observed in the Progesterone assay and approximately 5% cross-reactivity to T3 is observed in the T4 assay. No other significant cross-reactivity is observed within the panel or to other similar analytes.

Features and Benefits

Features:

  • Multiplex detection of 6 hormones in a single assay
  • Cross-species compatibility for rodents, primates, and other models
  • Magnetic bead-based format for efficient and reproducible processing
  • High sensitivity for low-abundance endocrine markers



Benefits:

  • Conserves sample volume and reagents through multiplexing
  • Enables comprehensive profiling of hormonal status
  • Supports translational and comparative endocrinology research
  • Provides robust, quantitative data for statistical analysis

Other Notes

Replaces: STTHMAG-21K

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Target Organs

Respiratory Tract

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Please refer to KIT Component information

PRTR

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FSL

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ISHL Indicated Name

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ISHL Notified Names

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Cartagena Act

Please refer to KIT Component information

JAN Code

キットコンポーネントの情報を参照してください

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gabriela Leite et al.
Menopause (New York, N.Y.), 29(3), 264-275 (2022-02-26)
Hormone therapy (HT) is used to treat menopause-related conditions and symptoms. The small intestine plays key roles in metabolic and endocrine function, but the effects of HT on the small intestinal microbiome are unknown. Here, we characterize duodenal microbiome differences
Christian K Garcia et al.
PloS one, 17(10), e0275715-e0275715 (2022-10-14)
The capability of male mice to exercise in hot environments without succumbing to exertional heat stroke (EHS) is markedly blunted compared to females. Epidemiological evidence in humans and other mammals also suggests some degree of greater vulnerability to heat stroke

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