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Merck

28-5730

Sulfanilamide

JIS special grade, ≥99.7%

Synonym(s):

p-Aminobenzenesulfonamide

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About This Item

Linear Formula:
H2NC6H4SO2NH2
CAS Number:
63-74-1
Molecular Weight:
172.20
EC Number:
200-563-4
UNSPSC Code:
12352005
PubChem Substance ID:
329753243
Beilstein/REAXYS Number:
511852
MDL number:
MFCD00007939
Assay:
≥99.7%
Grade:
JIS special grade
Form:
solid

Key Documents

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InChI key

FDDDEECHVMSUSB-UHFFFAOYSA-N

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

SMILES string

Nc1ccc(cc1)S(N)(=O)=O

grade

JIS special grade

assay

≥99.7%

form

solid

availability

available only in Japan

mp

164-166 °C (lit.)

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

DNA synthesis | interferes, enzyme | inhibits

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General description

Chemical structure: sulfonamide

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

28-5730-5-500G-J: + 28-5730-2-25G-J:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
U0259
U9148
U8059
U2980
U3945

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Xian-Long Wang et al.
European journal of medicinal chemistry, 45(10), 4631-4639 (2010-08-17)
A series of novel sulfanilamide-derived 1,2,3-triazole compounds were synthesized in excellent yields via 1,3-dipolar cycloaddition and confirmed by MS, IR and NMR spectra as well as elemental analyses. All the compounds were screened in vitro for their antibacterial and antifungal
Fei Liu et al.
Organic letters, 12(4), 868-871 (2010-01-19)
The synthesis of benzofused sultams and/or fluorinated sulfonamides, starting from N-allylic sulfonamides, was performed in superacid HF/SbF(5), through superelectrophilic activation. A dramatic effect of superacid composition on the selectivity of the reaction was shown and applied to the synthesis of
Ramazan Demirdağ et al.
Bioorganic & medicinal chemistry, 21(6), 1522-1525 (2012-09-15)
Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA) was purified 227.61-fold with a yield of 60.75%, and a specific activity of
Patricia Texeira Santana et al.
Journal of innate immunity, 7(4), 417-427 (2015-02-14)
Sepsis is associated with high mortality rates in intensive care units worldwide and represents a systemic inflammatory response to infection. P2X7 is an ionotropic purine receptor with known proinflammatory activity. Here, we investigated the role of the P2X7 receptor in
Sevgi Kolayli et al.
Journal of enzyme inhibition and medicinal chemistry, 26(6), 895-900 (2011-03-09)
An α-carbonic anhydrase (CA, EC 4.2.1.1) was purified and characterized kinetically from erythrocytes of the sturgeon Acipenser gueldenstaedti, an endangered species. The sturgeon enzyme (AgCA) showed kinetic parameters for the CO(2) hydration reaction comparable with those of the human erythrocytes
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