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Merck

175633

Silicone oil

for oil baths (from -40°C to +230°C)

Synonym(s):

Poly(dimethylsiloxane-co-methylphenylsiloxane)

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About This Item

Linear Formula:
[Si(CH3)2O]x[Si(CH3)(C6H5)O]y
CAS Number:
63148-52-7
UNSPSC Code:
12352100
PubChem Substance ID:
24850517
NACRES:
NA.21
MDL number:
MFCD00133270

Key Documents

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Product Name

Silicone oil, high temperature

InChI

1S/C7H8OSi.C2H6OSi/c1-9(8)7-5-3-2-4-6-7;1-4(2)3/h2-6H,1H3;1-2H3

InChI key

XWFOTLCDICUQTI-UHFFFAOYSA-N

SMILES string

C[Si](C)=O.C[Si](=O)c1ccccc1

vapor pressure

<5 mmHg ( 25 °C)

parameter

−40-450 °F temp. range (−40-230 °C)

refractive index

n20/D 1.495

density

1.05 g/mL at 25 °C

Quality Level

200

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Application

Silicone oil has been used as a medium component in containerless protein crystallization techniques which do not require contact with a solid surface. It was used as an oil bath during the synthesis of methyl 2-methylazulene-1-carboxylate.

General description

Silicone oil is a highly viscous oil made up of poly(dimethylsiloxane-co-methylphenylsiloxane) chains.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

437.0 °F - closed cup

flash_point_c

225.00 °C - closed cup

ppe

Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 4 petroleums + Hazardous rank III

fsl

175633-500G: + 175633-1KG: + 175633-100G: + 175633-VAR: + 175633-2.5KG: + 175633-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP7764
MKCP4724
MKCN6879
MKCN0797
MKCM0958

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Hui-Ling Cao et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 10), 1901-1910 (2013-10-09)
High-quality crystals are key to obtaining accurate three-dimensional structures of proteins using X-ray diffraction techniques. However, obtaining such protein crystals is often a challenge. Several containerless crystallization techniques have been reported to have the ability to improve crystal quality, but
Colloidal ordering from phase separation in a liquid-crystalline continuous phase.
Loudet J-C, et al.
Nature, 407(6804), 611-613 (2000)
Viscous liquid film flows over a periodic surface.
Trifonov YY.
International Journal of Multiphase Flow, 24(7), 1139-1161 (1999)
Jennifer Li et al.
The European journal of neuroscience, 34(12), 1983-1996 (2011-12-14)
Neuronal activity elicits metabolic and vascular responses, during which oxygen is first consumed and then supplied to the tissue via an increase in cerebral blood flow. Understanding the spatial and temporal dynamics of blood and tissue oxygen (To₂) responses following
Donald D Nolting et al.
Nature protocols, 4(8), 1113-1117 (2009-07-21)
Azulene has been recognized for its application in medicinal therapy against inflammation. Recently, azulene analogs have been used in optical technology. Nevertheless, synthesis of this family of compounds is always associated with multiple challenges. In this protocol, we describe a
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