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Merck

309052

Quinoline Yellow

Mixture of the mono- and disulfonic acids of Quinoline Yellow

Synonym(s):

Acid Yellow 3

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About This Item

CAS Number:
8004-92-0
MDL number:
MFCD00080727
UNSPSC Code:
12171500
NACRES:
NA.47
Colour Index Number:
47005

Key Documents

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Quality Level

200

form

powder

technique(s)

titration: suitable

solubility

H2O: soluble, spirit: soluble (23,413-3)

λmax

412 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[S](=O)(=O)([O-])c1c2nc(ccc2cc(c1)[S](=O)(=O)[O-])C3C(=O)c4c(cccc4)C3=O

InChI

1S/C18H11NO8S2.2Na/c20-17-11-3-1-2-4-12(11)18(21)15(17)13-6-5-9-7-10(28(22,23)24)8-14(16(9)19-13)29(25,26)27;;/h1-8,15H,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2

InChI key

FZUOVNMHEAPVBW-UHFFFAOYSA-L

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General description

Quinoline Yellow is a yellow, water-soluble, anionic quinophthalone dye. This synthetic dye is generally used as a food additive. Its applications are also seen in the cosmetic and pharmaceutical industries. It is a chinophthalon derivative applied in the compositions of skin, lips, or body cosmetics.Studies show that Quinoline Yellow is not genotoxic or carcinogenic. It is considered to be safe for human health.

Application

Quinoline Yellow has been used as an absorber for the fabrication of the micro-phantoms.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

309052-100G: + 309052-VAR: + 309052-25G: + 309052-BULK:

jan

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A Weisz et al.
Journal of chromatography. A, 923(1-2), 87-96 (2001-08-21)
The main components of the color additive D&C Yellow No. 10 (Quinoline Yellow, Color Index No. 47005), 2-(2-quinolinyl)-1H-indene-1,3(2H)-dione-6'-sulfonic acid (6SA) and 2-(2-quinolinyl)-1H-indene-1,3(2H)-dione-8'-sulfonic acid (8SA), were isolated from the dye mixture by pH-zone-refining counter-current chromatography (CCC) in the ion-exchange mode. These
Karen Lau et al.
Toxicological sciences : an official journal of the Society of Toxicology, 90(1), 178-187 (2005-12-15)
Exposure to non-nutritional food additives during the critical development window has been implicated in the induction and severity of behavioral disorders such as attention deficit hyperactivity disorder (ADHD). Although the use of single food additives at their regulated concentrations is
Quinoline Yellow dye-induced fixed food-and-drug eruption.
Camille Leleu et al.
Contact dermatitis, 68(3), 187-188 (2013-02-21)
Methyldopa-induced skin rash.
G Gidseg
Southern medical journal, 79(3), 389-389 (1986-03-01)
Hisao Oka et al.
Journal of chromatography. A, 989(2), 249-255 (2003-03-26)
Quinoline yellow (Color Index No. 47005) consists of multiple components that show a large difference in their partition coefficients (K), ranging from 0.03 to 3.3 in the solvent system tert.-butyl methyl ether (MTBE)-1-butanol-acetonitrile-aqueous 0.1 M trifluoroacetic acid (TFA). Consequently, it
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