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Merck

43791

2,2′-Dithiodipyridine

≥99.0% (GC)

Synonym(s):

2,2′-Dipyridyl disulfide

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About This Item

Empirical Formula (Hill Notation):
C10H8N2S2
CAS Number:
Molecular Weight:
220.31
UNSPSC Code:
12352112
NACRES:
NA.25
PubChem Substance ID:
EC Number:
218-343-1
Beilstein/REAXYS Number:
154629
MDL number:
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Product Name

2,2′-Dithiodipyridine, ≥99.0% (GC)

InChI key

HAXFWIACAGNFHA-UHFFFAOYSA-N

InChI

1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

SMILES string

S(Sc1ccccn1)c2ccccn2

assay

≥99.0% (GC)

form

solid

mp

56-58 °C (lit.)
57-59 °C

storage temp.

2-8°C

Quality Level

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Other Notes

For the determination of sulfhydryl groups in biological materials

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Determination of sulfhydryl groups with 2,2'- or 4,4'-dithiodipyridine.
D R Grassetti et al.
Archives of biochemistry and biophysics, 119(1), 41-49 (1967-03-01)
Rachel Lubong Sabado et al.
PloS one, 4(1), e4256-e4256 (2009-01-24)
The requirements for priming of HIV-specific T cell responses initially seen in infected individuals remain to be defined. Activation of T cell responses in lymph nodes requires cell-cell contact between T cells and DCs, which can give concurrent activation of
Sanae Haga et al.
Antioxidants & redox signaling, 11(10), 2563-2572 (2009-06-06)
Noninvasive evaluation of organ redox states provides invaluable information in many clinical settings. We evaluated a newly developed reduction/oxidation-sensitive green fluorescent protein (roGFP) probe that reports cellular redox potentials and their dynamic changes in live cells. On hypoxia/reoxygenation (H/R) of
T L Dutka et al.
The Journal of physiology, 589(Pt 9), 2181-2196 (2010-12-01)
S-Nitrosoglutathione (GSNO) is generated in muscle and may S-glutathionylate and/or S-nitrosylate various proteins involved in excitation–contraction (EC) coupling, such as Na+-K+-ATPases, voltage-sensors (VSs) and Ca2+ release channels (ryanodine receptors,RyRs), possibly changing their properties. Using mechanically skinned fibres from rat extensor
Claire Stines-Chaumeil et al.
The Biochemical journal, 395(1), 107-115 (2005-12-08)
Homotetrameric MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis catalyses the NAD-dependent oxidation of MMSA (methylmalonate semialdehyde) and MSA (malonate semialdehyde) into PPCoA (propionyl-CoA) and acetyl-CoA respectively via a two-step mechanism. In the present study, a detailed mechanistic characterization of the

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