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Merck

447293

5(6)-Carboxyfluorescein

Dye content 90 %

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About This Item

Empirical Formula (Hill Notation):
C21H12O7
CAS Number:
72088-94-9
Molecular Weight:
376.32
NACRES:
NA.47
PubChem Substance ID:
329756539
UNSPSC Code:
12171500
EC Number:
276-331-1
MDL number:
MFCD00151081

Key Documents

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InChI key

BPVHBBXCESDRKW-UHFFFAOYSA-N

InChI

1S/2C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21;22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h2*1-9,22-23H,(H,24,25)

SMILES string

OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35.OC(=O)c6ccc7C(=O)OC8(c9ccc(O)cc9Oc%10cc(O)ccc8%10)c7c6

assay

≥89.5% (HPLC)

form

powder

composition

Dye content, 90%

mp

275 °C (dec.) (lit.)

λmax

492 nm

ε (extinction coefficient)

12134 at 284 nm in 0.1 M NaOH at 0.005 g/L, 43060 at 239 nm in 0.1 M NaOH at 0.005 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

100

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Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

447293-BULK: + 447293-VAR: + 447293-5G: + 447293-1G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCK7036
MKCJ8194
MKCG6805
MKCD3055
MKBX5657V

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Jorien Claes et al.
Blood, 124(10), 1669-1676 (2014-06-22)
Adhesion of Staphylococcus aureus to blood vessels under shear stress requires von Willebrand factor (VWF). Several bacterial factors have been proposed to interact with VWF, including VWF-binding protein (vWbp), a secreted coagulase that activates the host's prothrombin to generate fibrin.
D Schuster et al.
Acta biomaterialia, 9(3), 5689-5697 (2012-11-22)
The work presented here shows for the first time that it is possible to silicify S-layer coated liposomes and to obtain stable functionalized hollow nano-containers. For this purpose, the S-layer protein of Geobacillus stearothermophilus PV72/p2 was recombinantly expressed and used
Jie Zhou et al.
Talanta, 99, 625-630 (2012-09-13)
A hairpin molecular beacon tagged with carboxyfluorescein in combination with graphene oxide as a quencher reagent was used to detect the DNA damage by chemical reagents. The fluorescence of molecular beacon was quenched sharply by graphene oxide; while in the
Suguru Nakagawa et al.
Investigative ophthalmology & visual science, 53(9), 5154-5160 (2012-06-15)
To investigate the toxicity profiles of seven antiglaucoma topical eye drops and benzalkonium chloride (BAC) using stratified cultivated human corneal epithelial cell sheets (HCES) in a serum-free culture system. A range of prostaglandin analogies and preservatives, including BAC, sofZia (SZ)
Martin Hossann et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 400-406 (2012-07-05)
Thermosensitive liposomes (TSL) are a promising tool for triggered drug delivery in combination with local hyperthermia. Objective of this study was to investigate the influence of serum on TSL in more detail and to identify serum components which are responsible
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