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Merck

50387

Acetonitrile

≥99.9% (GC), gradient grade, suitable for HPLC

Synonym(s):

Methyl cyanide, Anhydrous ACN, Dry MeCN

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About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
UNSPSC Code:
12190000
PubChem Substance ID:
EC Number:
200-835-2
Beilstein/REAXYS Number:
741857
MDL number:
eCl@ss:
39031501
Assay:
≥99.9% (GC)
Grade:
gradient grade
Technique(s):
HPLC: suitable
Bp:
81-82 °C (lit.)
Vapor pressure:
72.8 mmHg ( 20 °C)
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Product Name

Acetonitrile, suitable for HPLC, gradient grade, ≥99.9% (GC)

grade

gradient grade

Quality Level

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

assay

≥99.9% (GC)

form

liquid

autoignition temp.

973 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

16 %

technique(s)

HPLC: suitable

impurities

≤0.0005% free alkali (as NH3), ≤0.005% free acid (as CH3COOH), ≤0.02% water, ≤1 ppb quinine fluor., 254 nm, ≤1 ppb quinine fluor., 365 nm

evapn. residue

≤0.001%

refractive index

n20/D 1.344

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

density

0.786 g/mL at 25 °C (lit.)

absorption

≤1 mAU at 254 nm, ≤5 mAU at 210 nm

λ

1 cm path, H2O reference

UV absorption

λ: 200 nm Amax: 0.1, λ: 210 nm Amax: 0.035, λ: 220 nm Amax: 0.02, λ: 230 nm Amax: 0.01, λ: 240 nm Amax: 0.005

application(s)

food and beverages

format

neat

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N



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pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified



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Purification of acetonitrile.
Walter M and Ramaley L.
Analytical Chemistry, 45(1), 165-166 (1973)
Michelangelo Anastassiades et al.
Journal of AOAC International, 86(2), 412-431 (2003-05-02)
A simple, fast, and inexpensive method for the determination of pesticide residues in fruits and vegetables is introduced. The procedure involves initial single-phase extraction of 10 g sample with 10 mL acetonitrile, followed by liquid-liquid partitioning formed by addition of
Timo Glatter et al.
Molecular systems biology, 5, 237-237 (2009-01-22)
Protein complexes represent major functional units for the execution of biological processes. Systematic affinity purification coupled with mass spectrometry (AP-MS) yielded a wealth of information on the compendium of protein complexes expressed in Saccharomyces cerevisiae. However, global AP-MS analysis of