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Merck

71726

Sodium dodecyl sulfate

greener alternative

suitable for ion pair chromatography, LiChropur™, ≥99.0%

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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About This Item

Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
151-21-3
Molecular Weight:
288.38
NACRES:
NB.21
PubChem Substance ID:
329763468
eCl@ss:
39093306
UNSPSC Code:
23151816
EC Number:
205-788-1
MDL number:
MFCD00036175
Beilstein/REAXYS Number:
3599286

Key Documents

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Product Name

Sodium dodecyl sulfate, suitable for ion pair chromatography, LiChropur™, ≥99.0%

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

description

anionic
 62

assay

≥99.0% (GC)
≥99.0%

form

rod

quality

LiChropur™

mol wt

288.38 g/mol

Quality Level

100

greener alternative product characteristics

Catalysis
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technique(s)

ion pair chromatography: suitable

mp

204-207 °C (lit.)

solubility

water: soluble

λ

10 % in H2O

UV absorption

λ: 210 nm Amax: 0.1
λ: 220 nm Amax: 0.06
λ: 230 nm Amax: 0.04
λ: 260 nm Amax: 0.02
λ: 500 nm Amax: 0.02

HLB

40

suitability

corresponds to standard for RP gradient test
corresponds to standard for filter test

greener alternative category

Aligned

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Application

Anionic detergent
SDS may be used:
  • in peptide mapping and protein analysis by gel electrophoresis.
  • to utilize in designing formulations and its effect on adsorption and micellization parameters.
  • in measuring protein-SDS complexes and SDS solution in guanidine hydrochloride using gel chromatography.
  • in seperating protein subunits dissociated with SDS using Hydroxylapatite chromatography.

General description

Sodium dodecyl sulfate (SDS) is a detergent suitable to denature proteins. It is a long-chain aliphatic group which has negatively charged sulfate, hence making it amphipathic detergent in nature.
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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG9220
BCCG1231
BCCF3501
BCCD1342
BCCC4714

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Micellization behaviour of sodium dodecyl sulfate in different electrolyte media.
Umlong, I. M., and K. Ismail.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 299, 8-14 (2007)
Hydroxylapatite chromatography of protein-sodium dodecyl sulfate complexes. A new method for the separation of polypeptide subunits.
B Moss et al.
The Journal of biological chemistry, 247(16), 5194-5198 (1972-08-25)
Gel chromatography of proteins in denaturing solvents. Comparison between sodium dodecyl sulfate and guanidine hydrochloride as denaturants.
W W Fish et al.
The Journal of biological chemistry, 245(19), 5166-5168 (1970-10-10)
D. Shi
Biomedical Devices and Their Applications, 64-64 (2004)
D W Cleveland et al.
The Journal of biological chemistry, 252(3), 1102-1106 (1977-02-10)
A rapid and convenient method for peptide mapping of proteins has been developed. The technique, which is especially suitable for analysis of proteins that have been isolated from gels containg sodium dodecyl sulfate, involves partial enzymatic proteolysis in the presence
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Global Trade Item Number

SKUGTIN
71726-3CN04055977267471

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