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Merck

89595

Chlorotrimethylsilane

derivatization grade (GC derivatization), LiChropur™, ≥99.0% (GC)

Synonym(s):

TMCS, Trimethylchlorosilane, Trimethylsilyl chloride

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About This Item

Linear Formula:
(CH3)3SiCl
CAS Number:
75-77-4
Molecular Weight:
108.64
UNSPSC Code:
41115711
NACRES:
NA.22
PubChem Substance ID:
329769751
EC Number:
200-900-5
Beilstein/REAXYS Number:
1209232
MDL number:
MFCD00000502
Assay:
≥99.0% (GC)
Form:
liquid

Key Documents

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SMILES string

C[Si](C)(C)Cl

InChI

1S/C3H9ClSi/c1-5(2,3)4/h1-3H3

InChI key

IJOOHPMOJXWVHK-UHFFFAOYSA-N

grade

derivatization grade (GC derivatization)

vapor density

3.7 (vs air)

vapor pressure

100 mmHg ( 25 °C)

assay

≥99.0% (GC)

form

liquid

autoignition temp.

752 °F

quality

LiChropur™

expl. lim.

6.4 %

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.387 (lit.)

bp

57 °C (lit.)

mp

−40 °C (lit.)

density

0.856 g/mL at 25 °C (lit.)

Quality Level

100

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General description

Chlorotrimethylsilane is a silylation reagent used in the derivatization of triglycerides into volatile fatty esters by gas chromatography (GC).

Application

Learn more in the Product Information

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

supp_hazards

EUH014

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

-18.4 °F - closed cup

flash_point_c

-28 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

89595-BULK: + 89595-10X1ML: + 89595-1ML-KC: + 89595-50ML: + 89595-10ML: + 89595-VAR:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH1603
BCCG8397
BCCF9524
BCCF3203
BCCD7941

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Chlorotrimethylsilane as a reagent for gas chromatographic analysis of fats and oils.
Eras J, et al.
Journal of Chromatography A, 918(1), 227-232 (2001)
Ainara Sistiaga et al.
PloS one, 9(6), e101045-e101045 (2014-06-26)
Neanderthal dietary reconstructions have, to date, been based on indirect evidence and may underestimate the significance of plants as a food source. While zooarchaeological and stable isotope data have conveyed an image of Neanderthals as largely carnivorous, studies on dental
Nil Tandogan et al.
PloS one, 9(6), e101429-e101429 (2014-07-01)
We present an automated method for isolating pure bacterial cultures from samples containing multiple species that exploits the cell's own physiology to perform the separation. Cells compete to reach a chamber containing nutrients via a constriction whose cross-sectional area only
Kathleen A Vermeersch et al.
PloS one, 10(2), e0118262-e0118262 (2015-02-18)
Recently, multicellular spheroids were isolated from a well-established epithelial ovarian cancer cell line, OVCAR-3, and were propagated in vitro. These spheroid-derived cells displayed numerous hallmarks of cancer stem cells, which are chemo- and radioresistant cells thought to be a significant
Zachariah M Norman et al.
ACS nano, 8(7), 7513-7521 (2014-06-25)
We report the evolution of electrical transport and grain size during the sintering of thin films spin-cast from soluble phosphine and amine-bound, chloride-terminated cadmium selenide nanocrystals. Sintering of the nanocrystals occurs in three distinct stages as the annealing temperature is
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