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Merck

A92902

L-Ascorbic acid

99%

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
50-81-7
Molecular Weight:
176.12
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
57653896
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:
MFCD00064328

Key Documents

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InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

biological source

synthetic

assay

99%

form

powder

optical activity

[α]25/D 19.0 to 23.0°, c = 10% in H2O

color

white to off-white

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

Quality Level

200

Gene Information

human ... SLC23A2(9962)

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General description

L-ascorbic acid is used as a food additive, browning inhibitor, flavor stabilizer, dough modifier and color stabilizer. Deficiency of ascorbic acid is associated with scurvy. L-ascorbic acid stimulates immune response and is implicated in the synthesis of collagen, carnitine and neurotransmitters.

Application

L-Ascorbic acid has been used:
  • as a component in osteogenic differentiation medium
  • in MesenCult medium for the differentiation of bone marrow stromal cells
  • as a standard for vitamin C assay
  • to prevent trihalomethanes formation potential (THMFP)

Biochem/physiol Actions

L-Ascorbic acid (L-AA) is a widely available and water-soluble compound. L-AA has an ability to inhibit the corrosion of mild steel.
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

A92902-25G: + A92902-500G: + A92902-100G: + A92902-2KG: + A92902-BULK: + A92902-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH1937
BCCG6071
WXBD5783V
BCCF9931
BCCF4918

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Nutrient oxidation in pork loin is influenced by feed supplementation and packing methods
Godziszewska J, et al.
J. Food Compos. Anal., 56, 18-24 (2017)
Vitamin C in human health and disease is still a mystery? An overview
Naidu KA
Nutrition Journal, 2(1), 7-7 (2003)
The Role of Melatonin Preconditioning on Survival of Bone Marrow-Derived Mesenchymal Stem Cells in Differentiation to Osteoblasts
Rafat A, et al.
Iranian Red Crescent Medical Journal (2018)
Evaluation of the inhibitor effect of L-ascorbic acid on the corrosion of mild steel
Ferreira ES, et al.
Materials Chemistry and Physics, 83(1) (2004)
Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones
Katoh-Fukui Y, et al
Bone, 120(, 219-231 (2019)
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Protocols

Neural Stem Cell Culture Protocols

Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.

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