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Merck

P2126

L-Phenylalanine

≥98%

Synonym(s):

(S)-2-Amino-3-phenylpropionic acid

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About This Item

Linear Formula:
C6H5CH2CH(NH2)CO2H
CAS Number:
63-91-2
Molecular Weight:
165.19
NACRES:
NA.26
PubChem Substance ID:
24898274
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-568-1
MDL number:
MFCD00064227
Beilstein/REAXYS Number:
1910408

Key Documents

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Product Name

L-Phenylalanine, reagent grade, ≥98%

InChI key

COLNVLDHVKWLRT-QMMMGPOBSA-N

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

SMILES string

N[C@@H](Cc1ccccc1)C(O)=O

grade

reagent grade

assay

≥98%

form

powder or crystals

color

white to off-white

mp

270-275 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

application(s)

detection

Quality Level

200

Gene Information

human ... CA1(759), CA14(23632), CA2(760), CA4(762), CA5A(763), CA7(766)

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Application

L-Phenylalanine has been used in Fluo-4 Ca2+-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.

Biochem/physiol Actions

L-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG7616
0000118731
0000108475
BCCD8224
0000091507

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Effect of Dried Blood Spot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis
Roanna S. George, Stuart J. Moat
Clinical Chemistry (2016)
AMINO ACIDS | Metabolism
Encyclopedia of Food and Color Additives, 197-206 (2003)
The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Anne Cathrine
Scientific Reports (2017)
Genetics in Medicine : Official Journal of the American College of Medical Genetics (2012)
Protein and Amino Acid Metabolism
ESSENTIALS OF MEDICINAL CHEMISTRY null
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