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Merck

P4100000

Pyridoxine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · HCl
CAS Number:
58-56-0
Molecular Weight:
205.64
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329820198
MDL number:
MFCD00012807
Beilstein/REAXYS Number:
3632435

Key Documents

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InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

pyridoxine

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

214-215 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Pyridoxine hydrochloride is a HCl salt of pyridoxine or vitamin B6. It is a water-soluble vitamin that plays an important role in the treatment of roughness, sunburn, acne, and itch of the skin. It can also be employed in the potential management of sideroblastic anemias, depression and other disorders.

Application

Pyridoxine hydrochloride may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

P4100000-100MG: + P4100000-1EA: + P4100000:

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Pyridoxine hydrochloride
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 12(9), 3451-3452 (2017)
Spectral diagnostics of the interaction between pyridoxine hydrochloride and bovine serum albumin in vitro
Zhang H, et al.
Molecular Biology Reports, 35(4), 699-705 (2008)
Electrochemical behaviour of pyridoxine hydrochloride (vitamin B6) at carbon paste electrode modified with crown ethers
Desai PB, et al.
Journal of Solid State Electrochemistry, 12(9), 1067-1075 (2008)
Spectrophotometric methods for the simultaneous analysis of meclezine hydrochloride and pyridoxine hydrochloride in bulk drug and pharmaceutical formulations
Arayne MS, et al.
Pakistan Journal of Pharmaceutical Sciences, 20(2), 149-156 (2007)
Simultaneous spectrophotometric analysis of a ternary mixture of pharmaceuticals?assay for meclozine hydrochloride, pyridoxine hydrochloride and caffeine
Sharma SC, et al.
Journal of Pharmaceutical and Biomedical Analysis, 7(3), 321-327 (1989)
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