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PHR1086

Acetanilide melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Acetanilide, N-Phenylacetamide

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About This Item

Linear Formula:
CH3CONHC6H5
CAS Number:
103-84-4
Molecular Weight:
135.16
NACRES:
NA.24
PubChem Substance ID:
329823108
eCl@ss:
39031308
UNSPSC Code:
41116107
EC Number:
203-150-7
MDL number:
MFCD00008674
Beilstein/REAXYS Number:
606468
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1004001

vapor density

4.65 (vs air)

vapor pressure

1 mmHg ( 114 °C)

API family

acetanilide

CofA

current certificate can be downloaded

autoignition temp.

1004 °F

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

304 °C (lit.)

mp

~Approximately 115 °C, 113-115 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(=O)Nc1ccccc1

InChI

1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)

InChI key

FZERHIULMFGESH-UHFFFAOYSA-N

General description

Acetanilide belongs to a class of compounds which are the active components of drugs exhibiting analgesic and antipyretic properties.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acetanilide has been used as a calibration standard for the development of a test for the evaluation of acetanilide by thermal analyses methods.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7127 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

flash_point_f

321.8 °F - closed cup

flash_point_c

161 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

PHR1086-1G:4.54817340185E12

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Universal standard protocols for temperature and material characterization calibration with pharmaceuticals by thermal analysis
Maheswaram MP, et al.
ASTM Spec Tech Publ, 10(1-2), 467-475 (2010)
Thermal analysis study on vaporization of some analgesics. Acetanilide and derivatives
Vecchio S, et al.
Thermochimica Acta, 420(1-2), 99-104 (2004)
Inclusion complexation of acetanilide into the β-cyclodextrin nanocavity: A computational approach
Prema D and Sivakumar K
Procedia Materials Science, 10(1-2), 467-475 (2015)
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