RDD029
Guanidine thiocyanate
for molecular biology, free-flowing, Redi-Dri™, ≥99.0%
Synonym(s):
GTC, Guanidine isothiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
NH2C(=NH)NH2 · HSCN
CAS Number:
Molecular Weight:
118.16
NACRES:
NA.28
UNSPSC Code:
12352107
Beilstein/REAXYS Number:
3563461
MDL number:
product line
Redi-Dri™
Quality Segment
assay
≥99.0%
quality
for molecular biology, free-flowing
mp
120-122 °C (lit.)
foreign activity
DNAse, none detected, RNAse, none detected
SMILES string
SC#N.NC(N)=N
InChI
1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
InChI key
ZJYYHGLJYGJLLN-UHFFFAOYSA-N
General description
Guanadine thiocyanate (GTC) is a chaotropic agent and strong denaturant that is used in research for protein degredation in vitro. This is useful for DNA or RNA isolation and purification. GTC is a key reagent for inactivation of endogenous DNases and RNase for molecular biology techniques used to isolate nucliec acids from tissues, cells, or viral genomes.
Application
Chaotropic agent and strong denaturant; solubilizes cells.
Guanidine thiocyanate is commonly used for research:
- to denature proteins in cell lysis buffer
- to isolate and purify RNA from cells and tissues
- to extract DNA from cellular and viral genomes
Biochem/physiol Actions
Guanadine thiocyanate is strong protein denaturant commonly combinded with phenol to lyse tissues, cells, and proteins during RNA isolation assay.
Features and Benefits
- Redi-Dri™ makes working with hygroscopic chemicals easier
- Controls moisture and powder remains free-flowing
- Safer to handle and weigh out for routine use in lab
- Eliminates clumps and maintains product moisture and quality attributes
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
Still not finding the right product?
Explore all of our products under Guanidine thiocyanate
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C
supp_hazards
Storage Class
8B - Non-combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.