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U1250

Urea

≥99.5%, pellets, ReagentPlus®

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
57-13-6
Molecular Weight:
60.06
NACRES:
NA.21
PubChem Substance ID:
57654718
UNSPSC Code:
12352100
EC Number:
200-315-5
MDL number:
MFCD00008022
Beilstein/REAXYS Number:
635724
Assay:
≥99.5%
Form:
pellets
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Product Name

Urea, ReagentPlus®, ≥99.5%, pellets

Quality Segment

300

product line

ReagentPlus®

assay

≥99.5%

form

pellets

mp

132-135 °C (lit.)

solubility

H2O: 8 M

density

1.335 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

General description

Urea is a chaotropic agent and is used for protein denaturation. It disturbs the hydrogen bonds in the secondary, tertiary and quaternary structure of proteins. Urea can also disturb hydrogen bonds present in DNA secondary structure.

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Urea has been used as a protein denaturing agent.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

U1250-1G: + U1250-BULK: + U1250-CH: + U1250-5KG: + U1250-10KG: + U1250-100G: + U1250-VAR: + U1250-1KG: + U1250-500G:

jan

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