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302031

Trifluoroacetic acid

suitable for HPLC, ≥99.0%

Synonym(s):

TFA

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About This Item

Linear Formula:
CF3COOH
CAS Number:
76-05-1
Molecular Weight:
114.02
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
329753348
EC Number:
200-929-3
Beilstein/REAXYS Number:
742035
MDL number:
MFCD00004169
Assay:
≥99.0%
Concentration:
≥99,0%
Form:
liquid
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vapor density

3.9 (vs air)

Quality Level

200

vapor pressure

97.5 mmHg ( 20 °C)

assay

≥99.0%

form

liquid

concentration

≥99,0%

technique(s)

HPLC: suitable, UV/Vis spectroscopy: suitable

impurities

<0.050% water

evapn. residue

<0.005%

refractive index

n20/D 1.3 (lit.)

pH

1 (20 °C, 10 g/L)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

solubility

water: soluble

density

1.489 g/mL at 20 °C (lit.)

λ

H2O reference

UV absorption

λ: 260 nm Amax: 1.0, λ: 270 nm Amax: 0.10, λ: 280 nm Amax: 0.05, λ: 290 nm Amax: 0.04, λ: 300 nm Amax: 0.03, λ: 320 nm Amax: 0.025

application(s)

food and beverages

SMILES string

OC(C(F)(F)F)=O

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

Application

Appropriate for trace environmental analysis.
Used as a:
  • Mobile phase component in the estimation of chlorogenic acid and rutin in Rosaceae extracts by HPLC
  • Solvent to extract rabbit plasma, followed by HPLC purification of plasma protein content
  • Mobile phase solvent for separation of amino acids extracted from sediments, prior to HPLC analysis

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pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

302031-1L:4.548173387871E12 + 302031-100ML:4.548173385389E12

jan

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Guangfa Shi et al.
Organic letters, 17(1), 38-41 (2014-12-18)
Direct trifluoromethylation of arenes using TFA as the trifluoromethylating reagent was achieved with Ag as the catalyst. This reaction not only provides a new protocol for aryl C-H trifluoromethylation, but the generation of CF3· from TFA may prove useful in
Kwang Su Kim et al.
ACS applied materials & interfaces, 5(9), 3591-3598 (2013-04-05)
Graphene-based electrochemical impedance sensors have recently received much attention due to their outstanding sensing capability and economic viability. In this study, we present a novel means of constructing an impedance sensing platform via harnessing intrinsic π-stacking interactions between probe protein
W C Mahoney et al.
The Journal of biological chemistry, 255(23), 11199-11203 (1980-12-10)
A method employing reverse phase high performance liquid chromatography has been developed for the purification of large denatured peptides. The cyanogen bromide fragments of hemoglobin alpha, beta, and gamma chains (13 to 91 residues in length) could be separated and
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