Skip to Content
Merck

D201863

1,4-Dioxane

ReagentPlus®, ≥99%, contains ≤25 ppm BHT as stabilizer

Synonym(s):

Diethylene oxide, Dioxane

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
123-91-1
Molecular Weight:
88.11
UNSPSC Code:
12352005
NACRES:
NA.21
PubChem Substance ID:
329798726
EC Number:
204-661-8
Beilstein/REAXYS Number:
102551
MDL number:
MFCD00006571
Assay:
≥99%
Technique(s):
thin layer chromatography (TLC): suitable
Vapor pressure:
27 mmHg ( 20 °C), 40 mmHg ( 25 °C)

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

SMILES string

C1COCCO1

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C), 40 mmHg ( 25 °C)

product line

ReagentPlus®

assay

≥99%

form

liquid

autoignition temp.

356 °F

contains

≤25 ppm BHT as stabilizer

expl. lim.

22 %

technique(s)

thin layer chromatography (TLC): suitable

Quality Level

100

pH

6.0-8 (20 °C, 500 g/L)

density

1.034 g/mL at 25 °C (lit.)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

1,4-Dioxane can be used as a solvent:
  • To synthesize 1,3-diamines and amino alcohols via 2-azaallyl anion benzylic ring-opening of aziridines.
  • In the RAFT polymerization of acryclic acid.
  • In the synthesis of cross-linked triblock copolymer hydrogels.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH019,EUH066

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

D201863-25ML: + D201863-BULK: + D201863-18L:4548173193847 + D201863-VAR: + D201863-25L: + D201863-10L: + D201863-20L:4548173193861 + D201863-2.5L: + D201863-4L:4548173193878 + D201863-6X1L: + D201863-500ML: + D20186-18L-CS: + D201863-1L:4548173193854 + D201863-18L-CS:

jan

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBN8020
SHBM7455
SHBM4144
SHBL5388
SHBL4193

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

High-toughness polycation cross-linked triblock copolymer hydrogels
Chen Y, et al.
Macromolecules, 50, 3637-3646 (2017)
Yimu Zhao et al.
Advanced healthcare materials, 8(5), e1801187-e1801187 (2019-02-10)
Due to escalating drug developmental costs and limitations of cardiotoxicity screening, there is an urgent need to develop robust in vitro 3D tissue culture platforms that can both facilitate the culture of human cardiac tissues and provide noninvasive functional readouts
Xiaohua Liu et al.
Biomaterials, 31(2), 259-269 (2009-09-29)
It remains a challenge to synthesize functional materials that can develop advanced scaffolding architectures for tissue engineering. In this study, a series of biodegradable amphiphilic poly(hydroxyalkyl (meth)acrylate)-graft-poly(l-lactic acid) (PHAA-g-PLLA) copolymers have been synthesized and fabricated into nano-fibrous scaffolds. These copolymers
Joshua J Pacheco et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(23), 8363-8367 (2014-06-10)
Terephthalic acid (PTA), a monomer in the synthesis of polyethylene terephthalate (PET), is obtained by the oxidation of petroleum-derived p-xylene. There is significant interest in the synthesis of renewable, biomass-derived PTA. Here, routes to PTA starting from oxidized products of
Daniel Gerrity et al.
Water research, 46(19), 6257-6272 (2012-10-16)
The performance of ozonation in wastewater depends on water quality and the ability to form hydroxyl radicals (·OH) to meet disinfection or contaminant transformation objectives. Since there are no on-line methods to assess ozone and ·OH exposure in wastewater, many
View All Related Papers

Articles

AdQPhos and Pd pre catalysts for alpha arylation reaction

Discover AdQPhos and its Pd pre-catalysts for selective α-arylation of diverse nucleophiles under mild aqueous conditions without hazardous solvents.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service