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Merck

F1635

Formaldehyde solution

contains 10-15% methanol as stabilizer, 37 wt. % in H2O

Synonym(s):

Formalin

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About This Item

Linear Formula:
HCHO
CAS Number:
50-00-0
Molecular Weight:
30.03
UNSPSC Code:
12352114
NACRES:
NA.21
PubChem Substance ID:
329799685
MDL number:
MFCD00003274
Beilstein/REAXYS Number:
1209228
Technique(s):
tissue processing: suitable
Bp:
97 °C
Vapor pressure:
52 mmHg ( 37 °C)

Key Documents

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vapor density

1.03 (vs air)

Quality Level

200

vapor pressure

52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

10-15% methanol as stabilizer

concentration

37 wt. % in H2O, 37-38%

technique(s)

tissue processing: suitable

impurities

≤0.03% free acid (as HCOOH)

color

APHA: ≤10

pH

2.8-4.0

bp

97 °C

mp

-15 °C

density

1.09 g/mL at 25 °C (lit.)

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

This product is 37wt% solution of formaldehyde in water. It contains 10-15% methanol as stabilizer.

Application

Formaldehyde solution has been used to prepare formaldehyde fixation/permeabilization solution that is employed to fix tissue samples.

Biochem/physiol Actions

Induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. Potent mutagen.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

target_organs

Eyes,Central nervous system, Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

133.0 °F - closed cup

flash_point_c

56.11 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Specified Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 2 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

F1635-1GA-C: + F1635-400MLPP: + F1635-BULK: + F1635-300ML: + F1635-55ML: + F1635-25ML:4548173315454 + F1635-200ML: + F1635-105ML: + F1635-500ML:4548173315461 + F1635-500ML-C: + F1635-90ML: + F1635-400ML: + F1635-4L:4548173315416 + F1635-VAR: + F1635-78ML: + F1635-1GA: + F1635-24ML:

jan

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Christopher Bruhn et al.
Genomics, proteomics & bioinformatics, 12(6), 255-265 (2014-12-03)
Cell cycle progression is coordinated with metabolism, signaling and other complex cellular functions. The investigation of cellular processes in a cell cycle stage-dependent manner is often the subject of modern molecular and cell biological research. Cell cycle synchronization and immunostaining
Omer Barkai et al.
Pain, 160(6), 1281-1296 (2019-04-02)
Endogenous inflammatory mediators contribute to the pathogenesis of pain by acting on nociceptors, specialized sensory neurons that detect noxious stimuli. Here, we describe a new factor mediating inflammatory pain. We show that platelet-derived growth factor (PDGF)-BB applied in vitro causes
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
G R Moore et al.
Neurology, 55(10), 1506-1510 (2000-11-30)
To determine the pathologic basis of areas not exhibiting signal of the short-T2 component of the T2 relaxation distribution in MS, as studied in formalin-fixed brain. A myelin-specific MRI signal would be of great importance in assessing demyelination in patients
Richard Brad Jones et al.
PLoS pathogens, 10(8), e1004287-e1004287 (2014-08-15)
Resting memory CD4+ T-cells harboring latent HIV proviruses represent a critical barrier to viral eradication. Histone deacetylase inhibitors (HDACis), such as suberanilohydroxamic acid (SAHA), romidepsin, and panobinostat have been shown to induce HIV expression in these resting cells. Recently, it
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Product Information Sheet - F1635

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