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Merck

04277

Sodium phosphate tribasic dodecahydrate

≥98%

Synonym(s):

TSP, Trisodium phosphate (tert) dodecahydrate, Trisodium phosphate dodecahydrate

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About This Item

Linear Formula:
Na3PO4 · 12H2O
CAS Number:
10101-89-0
Molecular Weight:
380.12
PubChem Substance ID:
57646747
UNSPSC Code:
12161700
NACRES:
NA.25
EC Number:
231-509-8
MDL number:
MFCD00149198
Assay:
≥98%
Form:
crystalline
Solubility:
boiling water: soluble 1 part, water: soluble 3.5 parts, alcohol: insoluble

Key Documents

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SMILES string

O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]P([O-])([O-])=O, O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]P([O-])([O-])=O

InChI key

ASTWEMOBIXQPPV-UHFFFAOYSA-K

InChI

1S/3Na.H3O4P.12H2O/c;;;1-5(2,3)4;;;;;;;;;;;;/h;;;(H3,1,2,3,4);12*1H2/q3*+1;;;;;;;;;;;;;/p-3

assay

≥98%

form

crystalline

impurities

≤0.001% heavy metals (as Pb), ≤2.5% free alkali (as NaOH)

solubility

boiling water: soluble 1 part, water: soluble 3.5 parts, alcohol: insoluble

density

1.62 g/mL at 25 °C

anion traces

chloride (Cl-): ≤0.01%, sulfate (SO42-): ≤0.01%

cation traces

As: ≤1 mg/kg, Fe: ≤10 mg/kg

Quality Level

200

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Application

Sodium phosphate tribasic dodecahydrate was used to prepare buffer solution used in the analysis of pyronaridine in human whole blood and plasma by using high-performance liquid chromatography.

Biochem/physiol Actions

Sodium phosphate tribasic also referred to as Trisodium phosphate or TSP is a widely used cleaning agent. Trisodium phosphate disrupts cytoplasmic as well as outer membranes of Salmonella enterica cells and hence prevents the spread of bacteria. Further, it is corrosion inhibitor for iron and inhibits the rate of the anodic iron dissolution reaction in unbuffered solutions.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

04277-25KG-H: + 04277-6X1KG: + 04277-2.5KG: + 04277-6X2.5KG: + 04277-50KG-H: + 04277-1KG: + 04277-VAR: + 04277-BULK: + 04277-25KG:

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Certificates of Analysis (COA)

Lot/Batch Number
STBK8193
STBK7219
STBK4988
STBJ8815
STBJ7625

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Y C Chen et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 39-46 (2001-03-20)
An improved high-performance liquid chromatography method using a diisopropyl-C14 reversed-phase column (Zorbax Bonus-RP column) and a liquid-liquid extraction technique with UV detection is presented for the analysis of pyronaridine in human whole blood and plasma. Tribasic phosphate buffer (50 mM
Behaviour of sodium silicate and sodium phosphate (tribasic) as corrosion inhibitors for iron.
R. D. Armstrong
J. Appl. Electrochem., 24, 1244-1248 (1994)
Balamurugan Sampathkumar et al.
Applied and environmental microbiology, 69(1), 122-129 (2003-01-07)
Trisodium phosphate (TSP) is now widely used during the processing of poultry and red meats, but the mechanism whereby it inactivates gram-negative bacteria such Salmonella spp. remains unclear. Thus, Salmonella enterica serovar Enteritidis (ATCC 4931) cells were treated with different
Santosh Lamichhane et al.
Analytical chemistry, 87(12), 5930-5937 (2015-05-20)
Metabolomic analyses of fecal material are gaining increasing attention because the gut microbial ecology and activity have an impact on the human phenotype and regulate host metabolism. Sample preparation is a crucial step, and in this study, we recommend a
Joshua C Cheng et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(26), 9689-9700 (2015-07-03)
Temporal summation of pain (TSP), the perception of increasingly greater pain evoked by repetitive noxious stimuli, is highly variable between individuals. Individuals with facilitated pain processing and/or reduced pain-modulatory capabilities are regarded as pronociceptive, whereas individuals with reduced pain processing
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