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238422

2-Bromohexadecanoic acid

Name: 2-Bromohexadecanoic acid
Brand: SIGMA

~97%, PPARδ agonist, solid

Synonym(s):

2-Bromopalmitic acid

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About This Item

Linear Formula:

CH₃(CH₂)₁₃CH(Br)CO₂H

CAS Number:

18263-25-7

Molecular Weight:

335.32

NACRES:

NA.77

PubChem Substance ID:

57648040

UNSPSC Code:

12352203

EC Number:

242-137-0

MDL number:

MFCD00004215

Beilstein/REAXYS Number:

1726517

Assay:

~97%

Form:

solid

Quality level:

100

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Properties

Product Name

2-Bromohexadecanoic acid, ~97%

assay

~97%

Quality Level

100

form

solid

SMILES string

CCCCCCCCCCCCCCC(Br)C(O)=O

InChI

1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)

InChI key

DPRAYRYQQAXQPE-UHFFFAOYSA-N

Gene Information

human ... PPARD(5467)

Description

General description

PPARδ (peroxisome proliferator-activated receptor, delta isoform) acts as a transcription factor for gene expression as well as playing a role in lipid metabolism regulation; activity of this receptor is ligand-regulated. 2-Bromohexadecanoic acid is a metabolically stable analoge of the fatty acid palmitic acid that has been shown to be a natural ligand for the PPARδ receptor. 2-Bromohexadecanoic acid has also been used in studies of fatty acid oxidation, palmitoylation, and glucose uptake.

Biochem/physiol Actions

2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

238422-BULK: + 238422-VAR: + 238422-10G: + 238422-50G:

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