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Merck

A2218

L-Ascorbic acid

meets USP testing specifications

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
50-81-7
Molecular Weight:
176.12
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
24890635
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:
MFCD00064328

Key Documents

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Product Name

L-Ascorbic acid, meets USP testing specifications

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

biological source

synthetic

agency

USP/NF
meets USP testing specifications

assay

99.0-100.5%

form

solid

technique(s)

cell culture | mammalian: suitable

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

application(s)

pharmaceutical (small molecule)

Quality Level

200

Gene Information

human ... SLC23A2(9962)

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Application

L-ascorbic acid has been used as a supplement in DMEM/F12/ osteoblast induction medium. It has also been used as a component in liquid Ham′s isolation media.

Biochem/physiol Actions

L-ascorbic acid (AA) can block and treat scurvy. It possesses antioxidant properties. In the fermentation of wine, AA acid serve as a food additive and antioxidant.
Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

General description

L-ascorbic acid (AA) is a naturally occurring C vitamer. It is soluble in water. It is present in fruits and vegetables.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000297258
0000297261
0000297258
0000297261
SLCM1765

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Compositional analysis of foods
Liquid Chromatography (2013)
An improved protocol for the isolation and cultivation of embryonic mouse myocytes
Rodgers LS, et al.
Cytotechnology, 59(2), 93-102 (2009)
Analysis of vitamins by liquid chromatography
Liquid Chromatography, 571-615 (2017)
1, 3, 2-Dioxathiolane oxides: epoxide equivalents and versatile synthons
Lohray BB and Bhushan V
Advances in Heterocyclic Chemistry, 68, 90-181 (1997)
Biological characteristics of muscle-derived satellite cells isolated from rats at different postnatal days
Yu R, et al.
Cytotechnology, 67(3), 397-408 (2015)
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