Key Documents

View All Documentation

A7506

L-Ascorbic acid

Name: <SC>L</SC>-Ascorbic acid
Brand: SIGMA

reagent grade, crystalline

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₆H₈O₆

CAS Number:

50-81-7

Molecular Weight:

176.12

UNSPSC Code:

12352209

NACRES:

NA.26

PubChem Substance ID:

24891246

EC Number:

200-066-2

Beilstein/REAXYS Number:

84272

MDL number:

MFCD00064328

Assay:

≥98% ( with iodine, titration)

Form:

crystalline

Grade:

reagent grade

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

synthetic

Quality Level

200

grade

reagent grade

assay

≥98% ( with iodine, titration)

form

crystalline

technique(s)

HPLC: suitable, cell culture | stem cell: suitable

color

white to slightly yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

storage temp.

room temp

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

Description

General description

L-Ascorbic acid biosynthetic pathway varies in plants, animals and fungi. It is synthesized from L-gulono-1,4-lactone by the action of enzyme L-gulono-1,4-lactone oxidase (GLO).

Application

L-Ascorbic acid has been used:

as a chondrogenic medium component for culturing bone-derived mesenchymal stem cells (BMSCs)(149)
as a reference standard in high-performance liquid chromatography system (HPLC)(150)
to test its effect on human gastric cancer GES-1 and AGS cells(151)

Biochem/physiol Actions

L-Ascorbic acid deficiency is associated with lack of L-gulono-1,4-lactone oxidase (GLO) enzyme. It elicits antioxidant functionality and gets oxidized to dehydroascorbate via ascorbyl radical intermediate. L-Ascorbic acid is essential for maintaining the redox balance. It is a cofactor for dopamine-β-hydroxylase and favors T cell proliferation, protects immune system and provides relief in common cold.

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Disclaimer

May darken in storage.

Still not finding the right product?

Explore all of our products under L-Ascorbic acid

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library