Skip to Content
Merck

A9511

Albumin from human serum

lyophilized powder, ≥97% (agarose gel electrophoresis)

Synonym(s):

HSA

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

CAS Number:
70024-90-7
UNSPSC Code:
12352202
eCl@ss:
42010201
EC Number:
274-272-6
NACRES:
NA.25
MDL number:
MFCD00081418
Biological source:
human
Assay:
≥97% (agarose gel electrophoresis)
Form:
lyophilized powder
Technique(s):
ELISA: suitable, tissue culture: suitable, western blot: suitable
Impurities:
HIV I and HIVII, HCV and HBsAg, tested negative

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

biological source

human

assay

≥97% (agarose gel electrophoresis)

form

lyophilized powder

mol wt

monomer calculated mol wt 66478 Da

technique(s)

ELISA: suitable, tissue culture: suitable, western blot: suitable

impurities

HIV I and HIVII, HCV and HBsAg, tested negative

solubility

H2O: soluble 50 mg/mL

UniProt accession no.

P02768

storage temp.

2-8°C

Quality Level

300

Gene Information

human ... ALB(213)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Albumin is the most copious protein in blood plasma. Liver produces human albumin.
Human albumin possess a molecular weight of 67 kDa.

Application

Albumin from human serum has been used:
  • to standardize the column for molecular-exclusion chromatography
  • to prepare the tobacco mosaic virus (TMV)-poly ethylene glycol (PEG8)-serum albumin (SA) particles
  • to analyze its modifications after oxidation using a Fenton system

Albumin-bound fluorescence was used in serum of patients with chronic renal failure.

Biochem/physiol Actions

Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator in liver disease. Oxidative modification of albumin is seen in advanced liver disease.
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

Preparation Note

Prepared using method IV of Cohn, E.J., et al., J. Am. Chem. Soc., 69, 1753 (1947).

Other Notes

View more information on human serum albumin.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

A9511-10G: + A9511-1G: + A9511-100MG: + A9511-5G: + A9511-VAR: + A9511-500MG: + A9511-BULK: + A9511-25G:

jan

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000295095
0000295096
0000295098
0000295093
0000295094

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Effects of Fenton Reaction on Human Serum Albumin: An In Vitro Study
Khosravifarsani M, et al.
Electron Physician, 8(9), 2970-2970 (2016)
Elham Behzadi et al.
International journal of nanomedicine, 14, 257-270 (2019-01-16)
Recently, nanomaterials have moved into biological and medicinal implementations like cancer therapy. Therefore, before clinical trials, their binding to plasma proteins like human serum albumin (HSA) and their cytotoxic effects against normal and cancer cell lines should be addressed. Herein
Daniele Sanna et al.
Inorganic chemistry, 48(13), 5747-5757 (2009-06-12)
The complexation of the VO(2+) ion in several systems that can model the physiological conditions of its transport in blood serum was studied using electron paramagnetic resonance (EPR) spectroscopy. Particularly, the ternary systems formed by (i) VO(2+) and two high-molecular-mass
Fibrillation and Polymorphism of Human Serum Albumin
Bio-nanoimaging, 345-362 (2014)
Serum albumin camouflage of plant virus based nanoparticles prevents their antibody recognition and enhances pharmacokinetics
Pitek A, et al.
Biomaterials, 89(7-8), 89-97 (2016)
View All Related Papers

Articles

Albumin in Cell Culture

Explore serum albumin's role in serum-free cell culture systems for biomanufacturing.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service