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Merck

C4654

Cytidine

BioReagent, suitable for cell culture, powder, ≥99%

Synonym(s):

Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside

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About This Item

Empirical Formula (Hill Notation):
C9H13N3O5
CAS Number:
65-46-3
Molecular Weight:
243.22
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24892710
EC Number:
200-610-9
Beilstein/REAXYS Number:
89173
MDL number:
MFCD00006545

Key Documents

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Product Name

Cytidine, BioReagent, suitable for cell culture, powder, ≥99%

InChI key

UHDGCWIWMRVCDJ-XVFCMESISA-N

InChI

1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

biological source

synthetic

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

210-220 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

Gene Information

mouse ... Uck1(22245)

Quality Level

300

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Application

Cytidine has been used as a component to prepare ribonucleoside stock solution to assess its effects on the anaerobic growth of several Bacillus mojavensis strains.
Cytidine has been used as a non-essential aminoacid component of minimal essential medium (MEM) to analyse interspecies somatic cell nucleus transfer (iSCNT)-derived blastocysts. It has also been used as a supplement in the culture medium of HeLa cells, to study the effects of cytidine addition on rods and rings (RR) induced by glutamine deprivation.

General description

Cytidine is a nucleoside molecule. It is formed when cytosine is attached to a ribose ring through a β-N1-glycosidic bond.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH0268
BCCG1564
BCCF4811
BCCF5438
BCCF4400

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Shramana Chatterjee et al.
Biochemical and biophysical research communications, 523(2), 348-353 (2019-12-24)
Protein cages have recently emerged as an extraordinary drug-delivery system due to its biocompatibility, biodegradability, low toxicity, ease to manipulate and engineer. We have reported earlier the formation and architecture of a do-decameric cage-like architecture of Vibrio cholerae acylphosphatase (VcAcP)
Filippo M Cernilogar et al.
Nucleic acids research, 47(17), 9069-9086 (2019-07-28)
Pioneer transcription factors (PTF) can recognize their binding sites on nucleosomal DNA and trigger chromatin opening for recruitment of other non-pioneer transcription factors. However, critical properties of PTFs are still poorly understood, such as how these transcription factors selectively recognize
Martha J Folmsbee et al.
Applied and environmental microbiology, 70(9), 5252-5257 (2004-09-04)
Bacillus mojavensis strains JF-2 (ATCC 39307), ROB2, and ABO21191(T) and Bacillus subtilis strains 168 (ATCC 23857) and ATCC 12332 required four deoxyribonucleosides or DNA for growth under strict anaerobic conditions. Bacillus licheniformis strains L89-11 and L87-11, Bacillus sonorensis strain TG8-8
Interspecies somatic cell nucleus transfer with porcine oocytes as recipients: A novel bioassay system for assessing the competence of canine somatic cells to develop into embryos
Sugimura S, et al.
Theriogenology, 72(4), 549-559 (2009)
G P Gerrits et al.
Clinical chemistry, 34(7), 1439-1442 (1988-07-01)
Disturbances in the metabolism of purines and pyrimidines in neurologically affected patients can be reflected by aberrant concentrations of nucleosides and nucleobases in cerebrospinal fluid (CSF). However, normal values, especially for children at different ages, are lacking. We collected 1000
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