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C5608

Collagen from rabbit skin

Bornstein and Traub Type I, powder

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About This Item

CAS Number:
9007-34-5
UNSPSC Code:
12352202
EC Number:
232-697-4
NACRES:
NA.61
MDL number:
MFCD00130825
Form:
powder
Biological source:
rabbit skin

Key Documents

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biological source

rabbit skin

description

acid soluble

form

powder

technique(s)

cell culture | stem cell: suitable

solubility

aqueous acid: ≤10 mg/mL, aqueous sodium acetate buffer: soluble (0.01-0.5M)

UniProt accession no.

Q28668

storage temp.

2-8°C

Quality Level

200

Gene Information

rabbit ... COL1A2(100008997)

General description

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Application

Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.

Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.

Preparation Note

Prepared with modification of Gallop, P.M.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

C5608-100MG-PW: + C5608-VAR: + C5608-BULK: + C5608-100MG:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
SLCB8921
SLCB2165
SLBV8166
SLBS5681
SLBR8926V

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