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Merck

F5506

Freund′s Adjuvant, Incomplete

liquid

Synonym(s):

FICA

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203

Key Documents

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Product Name

Freund′s Adjuvant, Incomplete, liquid

form

liquid

color

faintly yellow to yellow

storage temp.

2-8°C

Quality Level

300

Application

Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.
Freund′s adjuvant (incomplete) lacks the Mycobacteria found in Complete Freund′s Adjuvant so it minimizes the side-effects.Freund′s Adjuvant, Incomplete is used for boost injections. It was used to emulsify antigens that are injected into animals to produce monoclonal antibodies from the antiserum.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Other Notes

Each mL contains 0.85 mL paraffin oil and 0.15 mL mannide monooleate.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCM0014
SLCL2576
SLCJ8244
SLCK1609
SLCK6127

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Elisabeth J M Huijbers et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(11), 4535-4544 (2010-07-17)
Monoclonal antibody-based therapies have made an important contribution to current treatment strategies for cancer and autoimmune disease. However, the cost for these new drugs puts a significant strain on the health-care economy, resulting in limited availability for patients. Therapeutic vaccination
Alan Gillett et al.
PloS one, 4(11), e7773-e7773 (2009-11-17)
Multiple Sclerosis (MS) is a chronic inflammatory disease causing demyelination and nerve loss in the central nervous system. Experimental autoimmune encephalomyelitis (EAE) is an animal model of MS that is widely used to investigate complex pathogenic mechanisms. Transcriptional control through
Stephan Culemann et al.
Nature, 572(7771), 670-675 (2019-08-09)
Macrophages are considered to contribute to chronic inflammatory diseases such as rheumatoid arthritis1. However, both the exact origin and the role of macrophages in inflammatory joint disease remain unclear. Here we use fate-mapping approaches in conjunction with three-dimensional light-sheet fluorescence
Katrine Hygum et al.
PloS one, 6(5), e20638-e20638 (2011-06-10)
In humans, the cobalamin (Cbl) -binding protein transcobalamin (TC) transports Cbl from the intestine and into all the cells of the body, whereas the glycoprotein haptocorrin (HC), which is present in both blood and exocrine secretions, is able to bind
J Ziebuhr et al.
Journal of virology, 69(7), 4331-4338 (1995-07-01)
The RNA polymerase gene of human coronavirus (HCV) 229E encodes a large polyprotein that contains domains with motifs characteristic of both papain-like cysteine proteinases and proteinases with homology to the 3C proteinase of picornaviruses. In this study, we have, first
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