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Merck

F5881

Freund′s Adjuvant, Complete

cell suspension

Synonym(s):

FCA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00131105

Key Documents

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Product Name

Freund′s Adjuvant, Complete, cell suspension

Quality Level

300

form

cell suspension

color

amber

storage temp.

2-8°C

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Application

Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion.
Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.

Biochem/physiol Actions

The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Each mL of Complete Freund′s adjuvant contains 1 mg of Mycobacterium tuberculosis (H37Ra, ATCC 25177), heat killed and dried, 0.85 mL paraffin oil and 0.15 mL mannide monooleate.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL8515
SLCL4379
SLCL2573
SLCK7708
SLCK7706

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U Iqbal et al.
British journal of cancer, 103(10), 1606-1616 (2010-10-21)
Insulin-like growth factor-binding protein 7 (IGFBP7) is an abundant, selective and accessible biomarker of glioblastoma multiforme (GBM) tumour vessels. In this study, an anti-IGFBP7 single-domain antibody (sdAb) was developed to target GBM vessels for molecular imaging applications. Human GBM was
Sukjae Joshua Kang et al.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(5), 487-493 (2017-09-09)
The anterior cingulate cortex (ACC) is known for its role in perception of nociceptive signals and the associated emotional responses. Recent optogenetic studies, involving modulation of neuronal activity in the ACC, show that the ACC can modulate mechanical hyperalgesia. In
E L Brown et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 15(2), 156-164 (2009-01-22)
Methicillin-resistant Staphylococcus aureus is increasingly responsible for staphylococcal infections in the community. A large percentage of the community-acquired methicillin-resistant (CA-MRSA) strains in the USA produce Panton-Valentine leukocidin (PVL), which is associated with severe infections. The virulence of the clinical CA-MRSA
Suchandan Sikder et al.
The Journal of infectious diseases, 218(2), 324-335 (2017-12-14)
Acute rheumatic fever and rheumatic heart disease (ARF/RHD) have long been described as autoimmune sequelae of Streptococcus pyogenes or group A streptococcal (GAS) infection. Both antibody and T-cell responses against immunodominant GAS virulence factors, including M protein, cross-react with host
L Curtis et al.
Allergy, 57(7), 627-631 (2002-07-09)
Few studies have measured pigeon allergens in non pigeon coop environments. This study was conducted to determine approximate pigeon dropping allergen concentrations in indoor environments. Polyclonal antibody serum was prepared by injecting a rabbit three times with crude wild pigeon
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抗体は特定の抗原と結合し、ユニークな抗原－抗体複合体を形成します。この結合の性質や、強固かつ特異的なこの結合を分子的標識として研究に使用する方法について説明します。

An Introduction to Antibodies: Antigens, Epitopes and Antibodies

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Data Sheet - F5881
Product Information Sheet - F5881

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