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Merck

F6760

Fast Red TR Salt 1,5-naphthalenedisulfonate salt

Powder

Synonym(s):

4-Chloro-2-methylbenzenediazonium salt

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About This Item

Linear Formula:
C7H6N2Cl · C10H7O6S2
CAS Number:
51503-28-7
Molecular Weight:
440.88
NACRES:
NA.47
PubChem Substance ID:
329799757
UNSPSC Code:
12171500
MDL number:
MFCD00069543
Colour Index Number:
37085

Key Documents

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Product Name

Fast Red TR Salt 1,5-naphthalenedisulfonate salt,

InChI

1S/C10H8O6S2.2C7H6ClN2/c11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16;2*1-5-4-6(8)2-3-7(5)10-9/h1-6H,(H,11,12,13)(H,14,15,16);2*2-4H,1H3/q;2*+1/p-2

SMILES string

[O-]S(C1=CC=CC2=C1C=CC=C2S(O)(=O)=O)(=O)=O.ClC3=CC=C([N+]#N)C(C)=C3

InChI key

PSAWWJOJWWUTJJ-UHFFFAOYSA-L

form

powder

color

white to light yellow

solubility

H2O: 25 mg/mL, clear to slightly hazy

suitability

suitable (as Coupling Agent with Naphthol AS)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

Quality Level

200

Related Categories

Application

Fast Red TR Salt 1,5-naphthalenedisulfonate salt has been used for tartrate-resistant acid phosphatase (TRAP) staining in tissue sections. It has been used as a chromogen in APAAP (alkaline phosphatase-anti-alkaline phosphatase) procedure.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H371

Hazard Classifications

STOT SE 2

target_organs

Eyes

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SHBN4576
MKCJ9565
MKCD0656
MKBH2143
MKBF9879

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Gamma interferon treatment in vivo provokes accumulation of activated monocytes in the venous circulation of rats.
Steiniger B et al.
The American Journal of Pathology, 136, 967-967 (1990)
Estrogen receptor-related receptor alpha impinges on the estrogen axis in bone: potential function in osteoporosis.
Bonnelye E et al.
Endocrinology, 143, 3658-3658 (2002)
B Steiniger et al.
The American journal of pathology, 136(4), 967-978 (1990-04-01)
Activated monocytes forming intravascular clumps in the veins of most organs appeared in LEW rats after a 3-day intravenous treatment with recombinant rat gamma interferon. Phenotyping in situ and in cytospot preparations of perfusates revealed that the cells coexpressed the
Sai Krishna Srimadh Bhagavatham et al.
Scientific reports, 11(1), 15129-15129 (2021-07-25)
Rheumatoid Arthritis (RA) is a chronic autoimmune disease associated with inflammation and joint remodeling. Adenosine deaminase (ADA), a risk factor in RA, degrades adenosine, an anti-inflammatory molecule, resulting in an inflammatory bias. We present an integrative analysis of clinical data
Shyan-Yuan Kao et al.
Bone, 145, 115837-115837 (2021-01-02)
The bone encasing the inner ear, known as the otic capsule, is unique because it remodels little postnatally compared to other bones in the body. Previous studies established that osteoprotegerin (OPG) in the inner ear inhibits otic capsule remodeling. OPG

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