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G7504

Guanosine 3′,5′-cyclic monophosphate

≥98% (HPLC), powder, intracellular mediator

Synonym(s):

cGMP, cyclic GMP

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About This Item

Empirical Formula (Hill Notation):
C10H12N5O7P
CAS Number:
7665-99-8
Molecular Weight:
345.21
NACRES:
NA.77
PubChem Substance ID:
24895309
UNSPSC Code:
41106305
EC Number:
231-641-6
MDL number:
MFCD00070129
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
200
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Product Name

Guanosine 3′,5′-cyclic monophosphate, ≥98% (HPLC), powder

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white

solubility

0.2 M NaHCO3: 50 mg/mL

storage temp.

−20°C

SMILES string

NC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1

InChI

1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)

InChI key

ZOOGRGPOEVQQDX-UHFFFAOYSA-N

Biochem/physiol Actions

A major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides.
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

Features and Benefits

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

G7504-5MG: + G7504-VAR: + G7504-25MG: + G7504-100MG: + G7504-BULK:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
098K7415
097K5063
126K5055
026K7034
015K7037

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