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Merck

M2015

1-Stearoyl-rac-glycerol

≥99%

Synonym(s):

MG(18:0/0:0/0:0)[rac], 1-Monooctadecanoyl-rac-glycerol, rac-Glycerol 1-stearate, DL-α-Stearin, Monostearin

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About This Item

Linear Formula:
CH3(CH2)16COOCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
358.56
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
EC Number:
204-664-4
Beilstein/REAXYS Number:
1728685
MDL number:
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InChI key

VBICKXHEKHSIBG-UHFFFAOYSA-N

InChI

1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

biological source

synthetic (organic)

assay

≥99%

form

powder

functional group

phospholipid

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

Quality Level

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Related Categories

Application

Monostearin (1-Stearoyl-rac-glycerol) is used in the development of drug delivery vehicles such as nanoparticles and microemulsions.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

M2015-100MG: + M2015-VAR: + M2015-500MG: + M2015-5G: + M2015-BULK: + M2015-1G:

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Sheng Tan et al.
Drug design, development and therapy, 11, 3519-3529 (2017-12-22)
Erlotinib (ETB) is a well-established therapeutic for non-small-cell lung cancer (NSCLC). To overcome drug resistance and severe toxicities in the clinical application, redox-responsive and pH-sensitive nanoparticle drug delivery systems were designed for the encapsulation of ETB. Poly(acrylic acid)-cystamine-oleic acid (PAA-ss-OA)
Maria Christina Camasmie Peters et al.
Journal of drug targeting, 28(3), 259-270 (2019-09-07)
Nanocrystals and lipid-based nanosystems have the potential to play a crucial role in a significant shift in the treatment of ophthalmic diseases. These drug delivery systems allow overcoming the barriers imposed by anatomy and physiology of the organ of vision.
Min Fang et al.
International journal of nanomedicine, 7, 5395-5404 (2012-10-24)
Curcumin has a variety of pharmacological effects. However, poor water solubility and low oral bioavailability limit its clinical utility. A delivery system for nanostructured lipid carriers has been reported to be a promising approach to enhancing the oral absorption of
Laizhu Zhang et al.
Drug delivery, 23(9), 3529-3537 (2016-06-25)
Transdermal local anesthesia is one of the most applied strategies to avoid systemic adverse effects; there is an appealing need for a prolonged local anesthetic that would provide better bioavailability and longer pain relief with a single administration. Layer-by-layer (LBL)
Maria Chountoulesi et al.
Brain sciences, 10(6) (2020-06-06)
Multiple sclerosis (MS) is a chronic, autoimmune, neurodegenerative disease of the central nervous system (CNS) that yields to neuronal axon damage, demyelization, and paralysis. Although several drugs were designed for the treatment of MS, with some of them being approved

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